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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST1
All Species:
14.85
Human Site:
S94
Identified Species:
25.13
UniProt:
Q15672
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15672
NP_000465.1
202
20954
S94
A
G
G
G
G
G
S
S
S
G
G
G
S
P
Q
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
G93
G
G
G
A
G
G
G
G
S
S
S
G
G
G
S
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
S85
A
G
G
G
G
S
S
S
G
G
G
S
P
Q
S
Dog
Lupus familis
XP_862829
199
20704
S91
G
G
G
G
G
G
S
S
S
G
G
G
S
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P26687
206
21180
S98
G
G
G
G
G
G
S
S
S
G
G
G
S
P
Q
Rat
Rattus norvegicus
P97831
160
18106
K53
T
P
G
K
R
G
K
K
G
S
P
S
A
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
K106
P
N
P
G
K
R
G
K
K
A
S
P
S
S
Q
Chicken
Gallus gallus
NP_990070
190
20385
S83
G
G
G
G
G
S
S
S
G
G
G
S
P
Q
S
Frog
Xenopus laevis
P13903
166
18778
S59
K
R
N
K
K
A
S
S
T
G
S
S
P
Q
S
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
L101
P
H
R
D
G
G
L
L
K
R
R
R
R
M
R
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
P191
S
N
R
V
K
R
R
P
A
P
Y
E
V
E
L
Fruit Fly
Dros. melanogaster
P10627
490
54403
K348
R
K
P
R
R
R
L
K
R
K
P
S
K
T
E
Honey Bee
Apis mellifera
NP_001011637
366
42484
K239
N
A
S
S
T
K
T
K
M
R
R
K
S
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001099179
204
23479
K95
G
S
G
S
L
S
H
K
I
R
R
K
G
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
94
98.5
N.A.
95.1
66.3
N.A.
52.3
88.6
70.7
21.8
21.8
23.4
32.5
N.A.
46.5
Protein Similarity:
100
98
94
98.5
N.A.
95.6
72.7
N.A.
62.6
89.1
76.7
34.3
31.8
28.7
39.8
N.A.
55.3
P-Site Identity:
100
40
60
93.3
N.A.
93.3
13.3
N.A.
20
53.3
20
13.3
0
0
6.6
N.A.
20
P-Site Similarity:
100
40
60
93.3
N.A.
93.3
20
N.A.
20
53.3
26.6
20
13.3
6.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
8
0
8
0
0
8
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
36
43
58
43
50
43
15
8
22
43
36
29
15
15
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
0
15
22
8
8
36
15
8
0
15
8
0
0
% K
% Leu:
0
0
0
0
8
0
15
8
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
8
15
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
8
15
0
0
0
0
8
0
8
15
8
22
29
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
36
% Q
% Arg:
8
8
15
8
15
22
8
0
8
22
22
8
8
0
8
% R
% Ser:
8
8
8
15
0
22
43
43
29
15
22
36
36
8
36
% S
% Thr:
8
0
0
0
8
0
8
0
8
0
0
0
0
8
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _