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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSC22D1 All Species: 3.94
Human Site: T264 Identified Species: 14.44
UniProt: Q15714 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15714 NP_006013.1 1073 109659 T264 P V S R K L S T T G S S D S I
Chimpanzee Pan troglodytes XP_001138557 595 60312
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534128 1245 126705 A444 P G S R K L S A P G S A D S V
Cat Felis silvestris
Mouse Mus musculus P62500 1077 109792 T264 P V S R K L S T T G S S D G G
Rat Rattus norvegicus NP_001103382 1050 106768 G252 V A S T S V P G G P P P T S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q91012 1040 105912 P235 A P V S A G P P P S P S F R K
Frog Xenopus laevis NP_001084750 708 73677
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.9 N.A. 77.5 N.A. 85.6 83.1 N.A. N.A. 66.1 28.7 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 35.3 N.A. 79.9 N.A. 89.3 87.1 N.A. N.A. 76.4 41.5 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 66.6 N.A. 86.6 13.3 N.A. N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 N.A. 80 N.A. 86.6 20 N.A. N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 0 0 15 0 0 15 0 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % F
% Gly: 0 15 0 0 0 15 0 15 15 43 0 0 0 15 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % I
% Lys: 0 0 0 0 43 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 43 15 0 0 0 0 29 15 29 15 29 15 0 0 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 43 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 58 15 15 0 43 0 0 15 43 43 0 43 0 % S
% Thr: 0 0 0 15 0 0 0 29 29 0 0 0 15 0 0 % T
% Val: 15 29 15 0 0 15 0 0 0 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _