KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSC22D1
All Species:
12.73
Human Site:
T465
Identified Species:
46.67
UniProt:
Q15714
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15714
NP_006013.1
1073
109659
T465
V
T
S
E
R
E
S
T
S
G
S
S
V
S
S
Chimpanzee
Pan troglodytes
XP_001138557
595
60312
A8
M
S
H
R
A
A
S
A
W
I
S
P
S
G
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534128
1245
126705
S645
T
S
E
R
E
S
T
S
G
S
S
V
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P62500
1077
109792
S465
Q
T
P
T
E
A
S
S
S
E
R
E
S
T
S
Rat
Rattus norvegicus
NP_001103382
1050
106768
S453
T
P
T
E
A
S
S
S
E
R
E
S
T
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91012
1040
105912
T436
V
T
S
E
R
E
S
T
S
G
S
S
V
S
S
Frog
Xenopus laevis
NP_001084750
708
73677
T121
G
L
A
N
Q
V
S
T
A
T
A
T
P
T
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.9
N.A.
77.5
N.A.
85.6
83.1
N.A.
N.A.
66.1
28.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.3
N.A.
79.9
N.A.
89.3
87.1
N.A.
N.A.
76.4
41.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
20
N.A.
26.6
26.6
N.A.
N.A.
100
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
40
N.A.
40
40
N.A.
N.A.
100
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
29
29
0
15
15
0
15
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% D
% Glu:
0
0
15
43
29
29
0
0
15
15
15
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
15
29
0
0
0
15
15
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
15
0
0
0
0
0
0
0
0
15
15
0
0
% P
% Gln:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
29
29
0
0
0
0
15
15
0
0
0
0
% R
% Ser:
0
29
29
0
0
29
86
43
43
15
58
43
43
58
58
% S
% Thr:
29
43
15
15
0
0
15
43
0
15
0
15
15
29
0
% T
% Val:
29
0
0
0
0
15
0
0
0
0
0
15
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _