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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSDHL
All Species:
16.97
Human Site:
S255
Identified Species:
41.48
UniProt:
Q15738
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15738
NP_001123237.1
373
41900
S255
I
L
A
A
E
Q
L
S
R
D
S
T
L
G
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082183
373
41749
S255
I
L
A
A
E
Q
L
S
R
D
L
T
L
G
G
Dog
Lupus familis
XP_853073
367
41423
S249
I
L
A
A
E
H
L
S
Q
D
T
A
V
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1J0
362
40667
S244
I
L
A
A
E
H
L
S
Q
D
A
A
L
G
G
Rat
Rattus norvegicus
Q5PPL3
362
40393
S244
I
L
A
A
E
H
L
S
R
D
A
G
L
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420279
346
38907
R227
I
L
A
A
E
H
L
R
K
D
S
P
V
C
G
Frog
Xenopus laevis
Q0IH73
386
43592
E239
A
A
E
A
L
T
S
E
K
K
Y
I
A
A
G
Zebra Danio
Brachydanio rerio
A8DZE7
387
43577
K239
A
A
D
A
L
T
E
K
Q
Q
C
R
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782978
298
32727
T181
M
V
P
T
L
V
Q
T
A
R
A
G
K
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53199
349
38688
L228
N
V
A
D
A
H
V
L
A
A
Q
K
L
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
86.3
N.A.
82
81.7
N.A.
N.A.
70.5
28.5
26.8
N.A.
N.A.
N.A.
N.A.
49.8
Protein Similarity:
100
N.A.
98.3
93.3
N.A.
89.8
90.3
N.A.
N.A.
84.1
46.8
48.3
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
N.A.
93.3
60
N.A.
73.3
80
N.A.
N.A.
60
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
93.3
80
N.A.
86.6
86.6
N.A.
N.A.
73.3
20
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
70
80
10
0
0
0
20
10
30
20
20
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
0
10
10
0
0
0
0
0
60
0
0
0
0
10
% D
% Glu:
0
0
10
0
60
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
20
0
40
80
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
20
10
0
10
10
0
10
% K
% Leu:
0
60
0
0
30
0
60
10
0
0
10
0
50
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
20
10
0
30
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
30
10
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
50
0
0
20
0
0
10
0
% S
% Thr:
0
0
0
10
0
20
0
10
0
0
10
20
0
10
0
% T
% Val:
0
20
0
0
0
10
10
0
0
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _