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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSDHL
All Species:
20
Human Site:
Y172
Identified Species:
48.89
UniProt:
Q15738
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15738
NP_001123237.1
373
41900
Y172
A
M
K
P
I
D
Y
Y
T
E
T
K
I
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082183
373
41749
Y172
A
M
K
P
I
D
Y
Y
T
E
T
K
I
L
Q
Dog
Lupus familis
XP_853073
367
41423
Y166
A
M
K
P
I
D
Y
Y
T
E
T
K
I
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1J0
362
40667
Y161
A
M
K
P
I
D
Y
Y
T
E
T
K
I
L
Q
Rat
Rattus norvegicus
Q5PPL3
362
40393
Y161
A
M
K
P
I
D
Y
Y
T
E
T
K
I
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420279
346
38907
P172
F
F
T
T
A
I
R
P
H
G
I
F
G
P
R
Frog
Xenopus laevis
Q0IH73
386
43592
R182
F
L
R
T
C
S
L
R
A
A
G
I
Y
G
P
Zebra Danio
Brachydanio rerio
A8DZE7
387
43577
V174
A
L
S
N
S
T
G
V
L
R
T
C
A
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782978
298
32727
M132
L
P
Y
A
T
S
F
M
D
S
Y
S
E
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53199
349
38688
S169
V
L
K
A
N
D
P
S
S
D
F
Y
T
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
86.3
N.A.
82
81.7
N.A.
N.A.
70.5
28.5
26.8
N.A.
N.A.
N.A.
N.A.
49.8
Protein Similarity:
100
N.A.
98.3
93.3
N.A.
89.8
90.3
N.A.
N.A.
84.1
46.8
48.3
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
0
0
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
6.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
20
10
0
0
0
10
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
60
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
50
0
0
10
0
0
% E
% Phe:
20
10
0
0
0
0
10
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
10
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
10
0
0
0
0
10
10
50
0
0
% I
% Lys:
0
0
60
0
0
0
0
0
0
0
0
50
0
0
10
% K
% Leu:
10
30
0
0
0
0
10
0
10
0
0
0
0
60
0
% L
% Met:
0
50
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
50
0
0
10
10
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
0
0
10
0
0
0
10
10
0
10
0
0
0
0
20
% R
% Ser:
0
0
10
0
10
20
0
10
10
10
0
10
0
0
0
% S
% Thr:
0
0
10
20
10
10
0
0
50
0
60
0
10
10
0
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
50
50
0
0
10
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _