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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR68
All Species:
11.52
Human Site:
T218
Identified Species:
31.67
UniProt:
Q15743
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15743
NP_003476.2
365
41077
T218
A
V
R
R
S
H
G
T
Q
K
S
R
K
D
Q
Chimpanzee
Pan troglodytes
P61072
352
39727
G207
Q
F
Q
H
I
M
V
G
L
I
L
P
G
I
V
Rhesus Macaque
Macaca mulatta
P79394
352
39721
G207
Q
F
Q
H
I
M
V
G
L
I
L
P
G
I
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFQ3
365
41190
T218
A
V
R
R
S
H
G
T
Q
K
S
R
K
D
Q
Rat
Rattus norvegicus
Q4KLH9
365
41249
T216
A
V
Q
S
S
V
S
T
E
R
Q
E
K
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514405
403
46335
T245
A
V
R
K
S
H
G
T
Q
K
N
R
K
S
Q
Chicken
Gallus gallus
P32250
308
35579
R163
R
Q
N
N
T
E
Q
R
T
C
F
E
N
F
P
Frog
Xenopus laevis
P35373
363
41522
I213
F
F
I
P
F
V
I
I
L
T
S
Y
T
L
I
Zebra Danio
Brachydanio rerio
XP_001339588
343
39519
V198
F
P
L
G
I
L
S
V
S
Y
F
R
V
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.2
27.9
N.A.
N.A.
92
45.7
N.A.
69.4
28.7
23.8
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.1
46.8
N.A.
N.A.
95.8
59.7
N.A.
76.6
45.2
45.7
65.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
N.A.
N.A.
100
33.3
N.A.
80
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
6.6
N.A.
N.A.
100
60
N.A.
93.3
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
12
% D
% Glu:
0
0
0
0
0
12
0
0
12
0
0
23
0
0
0
% E
% Phe:
23
34
0
0
12
0
0
0
0
0
23
0
0
12
0
% F
% Gly:
0
0
0
12
0
0
34
23
0
0
0
0
23
0
0
% G
% His:
0
0
0
23
0
34
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
34
0
12
12
0
23
0
0
0
23
12
% I
% Lys:
0
0
0
12
0
0
0
0
0
34
0
0
45
0
12
% K
% Leu:
0
0
12
0
0
12
0
0
34
0
23
0
0
23
0
% L
% Met:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
12
0
0
0
0
0
0
12
0
12
0
0
% N
% Pro:
0
12
0
12
0
0
0
0
0
0
0
23
0
0
12
% P
% Gln:
23
12
34
0
0
0
12
0
34
0
12
0
0
0
34
% Q
% Arg:
12
0
34
23
0
0
0
12
0
12
0
45
0
0
12
% R
% Ser:
0
0
0
12
45
0
23
0
12
0
34
0
0
12
0
% S
% Thr:
0
0
0
0
12
0
0
45
12
12
0
0
12
0
0
% T
% Val:
0
45
0
0
0
23
23
12
0
0
0
0
12
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _