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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR68 All Species: 11.52
Human Site: T218 Identified Species: 31.67
UniProt: Q15743 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15743 NP_003476.2 365 41077 T218 A V R R S H G T Q K S R K D Q
Chimpanzee Pan troglodytes P61072 352 39727 G207 Q F Q H I M V G L I L P G I V
Rhesus Macaque Macaca mulatta P79394 352 39721 G207 Q F Q H I M V G L I L P G I D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BFQ3 365 41190 T218 A V R R S H G T Q K S R K D Q
Rat Rattus norvegicus Q4KLH9 365 41249 T216 A V Q S S V S T E R Q E K V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514405 403 46335 T245 A V R K S H G T Q K N R K S Q
Chicken Gallus gallus P32250 308 35579 R163 R Q N N T E Q R T C F E N F P
Frog Xenopus laevis P35373 363 41522 I213 F F I P F V I I L T S Y T L I
Zebra Danio Brachydanio rerio XP_001339588 343 39519 V198 F P L G I L S V S Y F R V L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.2 27.9 N.A. N.A. 92 45.7 N.A. 69.4 28.7 23.8 49.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.1 46.8 N.A. N.A. 95.8 59.7 N.A. 76.6 45.2 45.7 65.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 0 N.A. N.A. 100 33.3 N.A. 80 0 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 6.6 N.A. N.A. 100 60 N.A. 93.3 6.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 12 % D
% Glu: 0 0 0 0 0 12 0 0 12 0 0 23 0 0 0 % E
% Phe: 23 34 0 0 12 0 0 0 0 0 23 0 0 12 0 % F
% Gly: 0 0 0 12 0 0 34 23 0 0 0 0 23 0 0 % G
% His: 0 0 0 23 0 34 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 34 0 12 12 0 23 0 0 0 23 12 % I
% Lys: 0 0 0 12 0 0 0 0 0 34 0 0 45 0 12 % K
% Leu: 0 0 12 0 0 12 0 0 34 0 23 0 0 23 0 % L
% Met: 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 12 0 0 0 0 0 0 12 0 12 0 0 % N
% Pro: 0 12 0 12 0 0 0 0 0 0 0 23 0 0 12 % P
% Gln: 23 12 34 0 0 0 12 0 34 0 12 0 0 0 34 % Q
% Arg: 12 0 34 23 0 0 0 12 0 12 0 45 0 0 12 % R
% Ser: 0 0 0 12 45 0 23 0 12 0 34 0 0 12 0 % S
% Thr: 0 0 0 0 12 0 0 45 12 12 0 0 12 0 0 % T
% Val: 0 45 0 0 0 23 23 12 0 0 0 0 12 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _