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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HERC1
All Species:
13.64
Human Site:
S223
Identified Species:
42.86
UniProt:
Q15751
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15751
NP_003913.3
4861
532186
S223
P
M
G
L
D
C
L
S
Q
V
T
T
F
L
K
Chimpanzee
Pan troglodytes
XP_001174017
4861
532381
S223
P
M
G
L
D
C
L
S
Q
V
T
T
F
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544717
4168
457081
Cat
Felis silvestris
Mouse
Mus musculus
Q4U2R1
4836
527512
F261
V
V
E
R
A
T
R
F
L
R
S
V
V
T
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514757
4866
533206
S223
P
M
G
L
D
C
L
S
Q
V
T
T
F
L
K
Chicken
Gallus gallus
XP_413753
4860
532952
S223
P
M
G
L
D
C
L
S
Q
V
T
T
F
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR91
4912
529978
R255
F
V
A
L
K
R
E
R
E
R
E
R
K
S
T
Honey Bee
Apis mellifera
XP_395007
4791
531039
V263
T
L
F
D
E
T
N
V
S
Q
V
W
L
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
84.1
N.A.
22.6
N.A.
N.A.
93.8
92.9
N.A.
N.A.
N.A.
22.7
22.3
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
84.9
N.A.
40.2
N.A.
N.A.
96.8
96.3
N.A.
N.A.
N.A.
39.3
39.9
N.A.
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
0
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
0
N.A.
13.3
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
50
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
13
0
13
0
13
0
13
0
13
0
0
13
0
% E
% Phe:
13
0
13
0
0
0
0
13
0
0
0
0
50
0
0
% F
% Gly:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
50
% K
% Leu:
0
13
0
63
0
0
50
0
13
0
0
0
13
50
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
13
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
13
13
13
0
25
0
13
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
13
0
13
0
0
13
0
% S
% Thr:
13
0
0
0
0
25
0
0
0
0
50
50
0
13
13
% T
% Val:
13
25
0
0
0
0
0
13
0
50
13
13
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _