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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC1A5
All Species:
1.21
Human Site:
S491
Identified Species:
2.67
UniProt:
Q15758
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15758
NP_005619.1
541
56598
S491
N
Y
V
D
R
T
E
S
R
S
T
E
P
E
L
Chimpanzee
Pan troglodytes
XP_512773
463
48192
I414
Q
S
L
D
F
V
K
I
I
T
I
L
V
T
A
Rhesus Macaque
Macaca mulatta
XP_001087755
367
39322
K318
H
L
N
Q
K
A
T
K
K
G
E
Q
E
L
T
Dog
Lupus familis
XP_541540
541
56794
L492
N
Y
V
D
R
T
E
L
R
S
S
V
P
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P51912
553
58464
M503
S
Y
V
D
R
T
K
M
P
S
S
E
P
E
L
Rat
Rattus norvegicus
P24942
543
59679
V494
D
S
L
G
A
G
I
V
E
H
L
S
R
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513313
363
39188
K314
Y
L
N
Q
K
E
M
K
K
A
E
R
E
L
S
Chicken
Gallus gallus
XP_001232900
531
55667
K481
N
Y
L
N
E
K
E
K
R
E
K
E
Q
E
L
Frog
Xenopus laevis
NP_001086093
527
55842
S477
A
G
L
L
Q
V
Y
S
D
R
T
S
S
S
N
Zebra Danio
Brachydanio rerio
XP_001341984
539
57802
N489
Y
L
I
D
R
H
P
N
K
N
E
E
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10901
503
54657
G452
N
V
L
G
D
A
M
G
A
G
I
V
Y
H
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
43.9
88.5
N.A.
79.5
38.4
N.A.
45.6
61.9
68.7
63
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
85.5
53.4
91.3
N.A.
86
61.6
N.A.
54.9
74.1
77.8
76.5
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
100
6.6
0
80
N.A.
66.6
0
N.A.
0
46.6
13.3
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
26.6
86.6
N.A.
86.6
13.3
N.A.
20
60
26.6
60
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
19
0
0
10
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
46
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
28
0
10
10
28
37
28
46
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
19
0
10
0
10
0
19
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
10
0
0
0
19
0
% H
% Ile:
0
0
10
0
0
0
10
10
10
0
19
0
0
0
0
% I
% Lys:
0
0
0
0
19
10
19
28
28
0
10
0
0
0
0
% K
% Leu:
0
28
46
10
0
0
0
10
0
0
10
10
0
19
46
% L
% Met:
0
0
0
0
0
0
19
10
0
0
0
0
0
0
0
% M
% Asn:
37
0
19
10
0
0
0
10
0
10
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
0
28
0
0
% P
% Gln:
10
0
0
19
10
0
0
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
37
0
0
0
28
10
0
10
10
0
0
% R
% Ser:
10
19
0
0
0
0
0
19
0
28
19
19
10
10
10
% S
% Thr:
0
0
0
0
0
28
10
0
0
10
19
0
0
10
10
% T
% Val:
0
10
28
0
0
19
0
10
0
0
0
19
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
37
0
0
0
0
10
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _