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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC1A5 All Species: 7.88
Human Site: T489 Identified Species: 17.33
UniProt: Q15758 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15758 NP_005619.1 541 56598 T489 L Q N Y V D R T E S R S T E P
Chimpanzee Pan troglodytes XP_512773 463 48192 V412 S Q Q S L D F V K I I T I L V
Rhesus Macaque Macaca mulatta XP_001087755 367 39322 A316 L H H L N Q K A T K K G E Q E
Dog Lupus familis XP_541540 541 56794 T490 L Q N Y V D R T E L R S S V P
Cat Felis silvestris
Mouse Mus musculus P51912 553 58464 T501 L Q S Y V D R T K M P S S E P
Rat Rattus norvegicus P24942 543 59679 G492 L G D S L G A G I V E H L S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513313 363 39188 E312 L H Y L N Q K E M K K A E R E
Chicken Gallus gallus XP_001232900 531 55667 K479 I L N Y L N E K E K R E K E Q
Frog Xenopus laevis NP_001086093 527 55842 V475 F G A G L L Q V Y S D R T S S
Zebra Danio Brachydanio rerio XP_001341984 539 57802 H487 L Q Y L I D R H P N K N E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10901 503 54657 A450 S I N V L G D A M G A G I V Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 43.9 88.5 N.A. 79.5 38.4 N.A. 45.6 61.9 68.7 63 N.A. N.A. N.A. 38.8 N.A.
Protein Similarity: 100 85.5 53.4 91.3 N.A. 86 61.6 N.A. 54.9 74.1 77.8 76.5 N.A. N.A. N.A. 58.9 N.A.
P-Site Identity: 100 13.3 6.6 80 N.A. 66.6 6.6 N.A. 6.6 33.3 13.3 33.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 33.3 33.3 86.6 N.A. 86.6 20 N.A. 26.6 53.3 26.6 60 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 19 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 46 10 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 28 0 10 10 28 37 28 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 10 0 19 0 10 0 10 0 19 0 0 0 % G
% His: 0 19 10 0 0 0 0 10 0 0 0 10 0 0 0 % H
% Ile: 10 10 0 0 10 0 0 0 10 10 10 0 19 0 0 % I
% Lys: 0 0 0 0 0 0 19 10 19 28 28 0 10 0 0 % K
% Leu: 64 10 0 28 46 10 0 0 0 10 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 19 10 0 0 0 0 0 % M
% Asn: 0 0 37 0 19 10 0 0 0 10 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 28 % P
% Gln: 0 46 10 0 0 19 10 0 0 0 0 0 0 10 10 % Q
% Arg: 0 0 0 0 0 0 37 0 0 0 28 10 0 10 10 % R
% Ser: 19 0 10 19 0 0 0 0 0 19 0 28 19 19 10 % S
% Thr: 0 0 0 0 0 0 0 28 10 0 0 10 19 0 0 % T
% Val: 0 0 0 10 28 0 0 19 0 10 0 0 0 19 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 19 37 0 0 0 0 10 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _