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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR19
All Species:
13.64
Human Site:
S308
Identified Species:
30
UniProt:
Q15760
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15760
NP_006134.1
415
47701
S308
H
E
Q
D
Y
K
K
S
S
L
V
F
T
A
I
Chimpanzee
Pan troglodytes
XP_001153454
415
47661
S308
H
E
Q
D
Y
K
K
S
S
L
V
F
T
A
I
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
P304
V
I
Q
D
N
L
I
P
K
E
V
Y
I
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q61121
415
47515
S308
H
E
Q
D
Y
K
K
S
S
L
V
F
T
A
V
Rat
Rattus norvegicus
P70585
415
47616
S308
H
E
Q
D
Y
R
K
S
S
L
V
F
T
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512718
423
48245
L315
L
N
C
Y
V
I
L
L
S
S
N
T
T
S
T
Chicken
Gallus gallus
Q9DDN6
385
43491
V280
M
L
V
C
V
V
V
V
F
A
V
S
W
L
P
Frog
Xenopus laevis
NP_001088695
423
48161
L315
L
N
C
Y
V
V
L
L
S
S
Q
T
I
R
T
Zebra Danio
Brachydanio rerio
NP_957288
413
46192
G306
P
R
G
S
G
R
Q
G
A
L
F
F
I
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
E353
L
Q
L
L
L
N
D
E
E
F
A
H
W
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200143
391
44101
V286
S
E
I
S
Q
S
E
V
N
I
Y
W
A
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
22.6
N.A.
N.A.
89.4
88.6
N.A.
22.9
24.5
25.2
62.8
N.A.
25
N.A.
N.A.
37.5
Protein Similarity:
100
98.3
45.2
N.A.
N.A.
93.7
93.2
N.A.
41.3
42.1
45.1
77.3
N.A.
43.5
N.A.
N.A.
57.8
P-Site Identity:
100
100
20
N.A.
N.A.
93.3
86.6
N.A.
13.3
6.6
6.6
13.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
20
6.6
6.6
40
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
10
0
10
37
0
% A
% Cys:
0
0
19
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
46
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
0
46
0
0
0
0
10
10
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
10
46
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
37
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
10
0
0
10
10
0
0
10
0
0
28
0
19
% I
% Lys:
0
0
0
0
0
28
37
0
10
0
0
0
0
0
0
% K
% Leu:
28
10
10
10
10
10
19
19
0
46
0
0
0
19
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
10
10
0
0
10
0
10
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
19
% P
% Gln:
0
10
46
0
10
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
0
0
0
19
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
0
0
19
0
10
0
37
55
19
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
19
46
19
19
% T
% Val:
10
0
10
0
28
19
10
19
0
0
55
0
0
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% W
% Tyr:
0
0
0
19
37
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _