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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPEG All Species: 13.64
Human Site: S706 Identified Species: 60
UniProt: Q15772 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15772 NP_005867.3 3267 354289 S706 P T S P E L E S S D D S Y V S
Chimpanzee Pan troglodytes XP_514255 2005 216367
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536083 3612 391371 S764 P T S P E L E S S D D S Y V S
Cat Felis silvestris
Mouse Mus musculus Q62407 3262 354324 S711 P T S P E L E S S D D S Y V S
Rat Rattus norvegicus Q63638 3259 354148 S711 P T S P E L E S S D D S Y V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q696W0 2995 333665 A646 C F I A G S Q A V D V D W L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.6 N.A. 82 N.A. 91.3 91.1 N.A. N.A. N.A. N.A. 39.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 32.3 N.A. 84.7 N.A. 93.9 93.7 N.A. N.A. N.A. N.A. 55.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 0 0 17 0 0 0 0 0 0 17 % A
% Cys: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 84 67 17 0 0 0 % D
% Glu: 0 0 0 0 67 0 67 0 0 0 0 0 0 0 0 % E
% Phe: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 67 0 0 0 0 0 0 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 67 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 67 0 0 17 0 67 67 0 0 67 0 0 67 % S
% Thr: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 17 0 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _