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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLF2 All Species: 21.21
Human Site: S103 Identified Species: 38.89
UniProt: Q15773 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15773 NP_005430.1 248 28147 S103 G G N C Q T F S S S T V I S Y
Chimpanzee Pan troglodytes XP_001154028 283 32140 C121 D P N G H S F C S S S V M T Y
Rhesus Macaque Macaca mulatta XP_001101964 282 32058 C120 D P N G H S F C S S S V M T Y
Dog Lupus familis XP_853524 248 28120 S103 G G N C Q T F S S S T V I S Y
Cat Felis silvestris
Mouse Mus musculus Q99KX1 247 28037 S102 G G N C Q T F S S S T V I S Y
Rat Rattus norvegicus NP_001101150 282 32202 C121 D P N G H S F C S S S V M T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518073 270 29614 S125 G A N C Q T F S S S T V I S Y
Chicken Gallus gallus NP_001025947 242 27468 F101 S G A N C Q T F T S S T V I S
Frog Xenopus laevis NP_001085349 242 27458 G98 N V D Q M T T G S N C Q T F S
Zebra Danio Brachydanio rerio NP_001020687 250 28397 S96 S P N C Q T F S S S T V I S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NKV0 376 41359 C103 G N S G A S F C Q S T V M T M
Honey Bee Apis mellifera XP_393366 257 29409 S97 A S S G N C H S F V S N S V M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796343 284 31913 S106 D P N S H C Y S S S S V M S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 34.7 97.9 N.A. 96.7 34.4 N.A. 75.5 84.2 66.9 58 N.A. 26.3 32.6 N.A. 39.4
Protein Similarity: 100 55.4 55.3 98.7 N.A. 97.5 52.1 N.A. 80.7 89.5 81 72.8 N.A. 38.8 50.1 N.A. 56.3
P-Site Identity: 100 40 40 100 N.A. 100 40 N.A. 93.3 13.3 13.3 86.6 N.A. 33.3 6.6 N.A. 46.6
P-Site Similarity: 100 66.6 66.6 100 N.A. 100 66.6 N.A. 93.3 33.3 26.6 86.6 N.A. 60 20 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 39 8 16 0 31 0 0 8 0 0 0 0 % C
% Asp: 31 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 70 8 8 0 0 0 0 8 0 % F
% Gly: 39 31 0 39 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 31 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 39 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 39 0 16 % M
% Asn: 8 8 70 8 8 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 39 8 0 0 8 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 8 16 8 0 31 0 54 77 85 47 0 8 47 16 % S
% Thr: 0 0 0 0 0 47 16 0 8 0 47 8 8 31 0 % T
% Val: 0 8 0 0 0 0 0 0 0 8 0 77 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _