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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF2
All Species:
29.39
Human Site:
S129
Identified Species:
53.89
UniProt:
Q15773
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15773
NP_005430.1
248
28147
S129
Q
E
T
S
E
M
R
S
A
P
G
G
I
R
E
Chimpanzee
Pan troglodytes
XP_001154028
283
32140
R147
Q
A
S
T
Q
T
R
R
A
P
G
G
I
K
E
Rhesus Macaque
Macaca mulatta
XP_001101964
282
32058
R146
Q
A
S
T
Q
T
R
R
A
P
G
G
I
K
E
Dog
Lupus familis
XP_853524
248
28120
S129
Q
E
T
S
E
M
R
S
A
P
G
G
I
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99KX1
247
28037
S128
Q
E
T
S
E
M
R
S
A
P
G
G
I
R
E
Rat
Rattus norvegicus
NP_001101150
282
32202
R147
Q
A
A
T
Q
T
R
R
A
P
G
G
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518073
270
29614
S151
H
E
T
S
E
M
R
S
A
P
G
G
I
R
E
Chicken
Gallus gallus
NP_001025947
242
27468
S127
Q
E
T
S
E
M
R
S
A
P
G
G
I
R
E
Frog
Xenopus laevis
NP_001085349
242
27458
Y124
G
V
S
A
P
K
V
Y
H
E
T
T
Q
T
R
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
T122
Q
Q
T
S
E
Y
R
T
A
P
G
G
I
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
T129
Q
A
S
T
S
T
K
T
G
P
G
G
V
R
E
Honey Bee
Apis mellifera
XP_393366
257
29409
T123
E
E
T
T
S
T
T
T
V
P
G
G
I
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
Q132
Q
A
S
S
S
T
R
Q
A
P
G
G
I
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
34.7
97.9
N.A.
96.7
34.4
N.A.
75.5
84.2
66.9
58
N.A.
26.3
32.6
N.A.
39.4
Protein Similarity:
100
55.4
55.3
98.7
N.A.
97.5
52.1
N.A.
80.7
89.5
81
72.8
N.A.
38.8
50.1
N.A.
56.3
P-Site Identity:
100
53.3
53.3
100
N.A.
100
46.6
N.A.
93.3
100
0
80
N.A.
40
46.6
N.A.
66.6
P-Site Similarity:
100
80
80
100
N.A.
100
73.3
N.A.
93.3
100
13.3
93.3
N.A.
73.3
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
8
8
0
0
0
0
77
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
47
0
0
47
0
0
0
0
8
0
0
0
0
93
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
93
93
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
77
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
0
0
0
0
0
31
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
39
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
93
0
0
0
0
0
% P
% Gln:
77
8
0
0
24
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
77
24
0
0
0
0
0
62
8
% R
% Ser:
0
0
39
54
24
0
0
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
54
39
0
47
8
24
0
0
8
8
0
8
0
% T
% Val:
0
8
0
0
0
0
8
0
8
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _