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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF2
All Species:
42.73
Human Site:
S146
Identified Species:
78.33
UniProt:
Q15773
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15773
NP_005430.1
248
28147
S146
R
T
V
R
D
S
D
S
G
L
E
Q
M
S
I
Chimpanzee
Pan troglodytes
XP_001154028
283
32140
S164
K
A
M
R
D
S
D
S
G
L
E
K
M
A
I
Rhesus Macaque
Macaca mulatta
XP_001101964
282
32058
S163
K
A
M
R
D
S
D
S
G
L
E
K
M
A
I
Dog
Lupus familis
XP_853524
248
28120
S146
R
T
V
R
D
S
D
S
G
L
E
Q
M
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99KX1
247
28037
S145
R
T
V
R
D
S
D
S
G
L
E
Q
M
S
I
Rat
Rattus norvegicus
NP_001101150
282
32202
S164
K
A
I
R
D
S
D
S
G
L
E
R
M
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518073
270
29614
S168
R
T
V
R
D
S
D
S
G
L
E
Q
M
S
I
Chicken
Gallus gallus
NP_001025947
242
27468
S144
R
T
V
R
D
S
D
S
G
L
E
Q
M
S
I
Frog
Xenopus laevis
NP_001085349
242
27458
R141
P
G
G
I
R
E
T
R
R
A
V
R
D
S
D
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
S139
Q
T
M
R
D
S
Q
S
G
L
E
R
M
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
T146
R
T
V
Q
D
S
R
T
G
V
K
K
M
A
I
Honey Bee
Apis mellifera
XP_393366
257
29409
T140
T
T
V
C
D
S
R
T
G
K
K
K
M
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
Q149
K
T
V
R
D
S
A
Q
G
I
E
K
M
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
34.7
97.9
N.A.
96.7
34.4
N.A.
75.5
84.2
66.9
58
N.A.
26.3
32.6
N.A.
39.4
Protein Similarity:
100
55.4
55.3
98.7
N.A.
97.5
52.1
N.A.
80.7
89.5
81
72.8
N.A.
38.8
50.1
N.A.
56.3
P-Site Identity:
100
66.6
66.6
100
N.A.
100
60
N.A.
100
100
6.6
73.3
N.A.
53.3
46.6
N.A.
60
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
93.3
N.A.
100
100
13.3
93.3
N.A.
93.3
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
0
0
0
8
0
0
8
0
0
0
47
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
93
0
62
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
77
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
93
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
85
% I
% Lys:
31
0
0
0
0
0
0
0
0
8
16
39
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% L
% Met:
0
0
24
0
0
0
0
0
0
0
0
0
93
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
8
8
0
0
0
39
0
0
0
% Q
% Arg:
47
0
0
77
8
0
16
8
8
0
0
24
0
0
0
% R
% Ser:
0
0
0
0
0
93
0
70
0
0
0
0
0
54
0
% S
% Thr:
8
70
0
0
0
0
8
16
0
0
0
0
0
0
0
% T
% Val:
0
0
62
0
0
0
0
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _