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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF2
All Species:
18.79
Human Site:
S201
Identified Species:
34.44
UniProt:
Q15773
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15773
NP_005430.1
248
28147
S201
D
E
W
R
R
E
T
S
R
F
R
Q
Q
R
P
Chimpanzee
Pan troglodytes
XP_001154028
283
32140
L219
E
E
W
Q
S
E
V
L
K
Y
K
P
G
R
H
Rhesus Macaque
Macaca mulatta
XP_001101964
282
32058
L218
E
E
W
Q
S
E
V
L
K
Y
K
P
G
R
H
Dog
Lupus familis
XP_853524
248
28120
S201
D
E
W
R
R
E
T
S
R
F
R
Q
Q
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99KX1
247
28037
S200
D
E
W
R
R
E
T
S
R
Y
R
Q
Q
R
P
Rat
Rattus norvegicus
NP_001101150
282
32202
L219
D
E
W
Q
N
E
V
L
K
Y
K
P
I
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518073
270
29614
S223
D
E
W
R
R
E
T
S
R
F
R
P
Q
R
P
Chicken
Gallus gallus
NP_001025947
242
27468
S199
D
E
W
R
R
E
T
S
R
F
R
P
Q
R
G
Frog
Xenopus laevis
NP_001085349
242
27458
D196
E
V
D
A
A
G
F
D
E
E
W
T
R
Q
T
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
G194
E
E
W
R
R
E
V
G
R
Y
R
P
P
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
S201
R
E
F
T
S
R
A
S
R
G
A
V
Q
S
R
Honey Bee
Apis mellifera
XP_393366
257
29409
R195
K
E
W
E
S
R
V
R
H
Y
G
N
Y
H
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
G204
N
E
W
K
Q
K
T
G
A
H
R
G
G
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
34.7
97.9
N.A.
96.7
34.4
N.A.
75.5
84.2
66.9
58
N.A.
26.3
32.6
N.A.
39.4
Protein Similarity:
100
55.4
55.3
98.7
N.A.
97.5
52.1
N.A.
80.7
89.5
81
72.8
N.A.
38.8
50.1
N.A.
56.3
P-Site Identity:
100
26.6
26.6
100
N.A.
93.3
26.6
N.A.
93.3
86.6
0
46.6
N.A.
26.6
13.3
N.A.
26.6
P-Site Similarity:
100
60
60
100
N.A.
100
53.3
N.A.
93.3
86.6
20
60
N.A.
33.3
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
8
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
31
93
0
8
0
70
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
31
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
16
0
8
8
8
24
16
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
24
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
8
0
8
0
0
24
0
24
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
47
8
0
31
% P
% Gln:
0
0
0
24
8
0
0
0
0
0
0
24
47
8
0
% Q
% Arg:
8
0
0
47
47
16
0
8
54
0
54
0
8
54
24
% R
% Ser:
0
0
0
0
31
0
0
47
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
47
0
0
0
0
8
0
8
8
% T
% Val:
0
8
0
0
0
0
39
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
85
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
47
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _