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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLF2 All Species: 28.48
Human Site: S238 Identified Species: 52.22
UniProt: Q15773 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15773 NP_005430.1 248 28147 S238 A I Q G P E D S P S R Q S R R
Chimpanzee Pan troglodytes XP_001154028 283 32140 S255 R R E K P Q Q S P A I E H G R
Rhesus Macaque Macaca mulatta XP_001101964 282 32058 S254 R R E K P Q Q S P A I E R G R
Dog Lupus familis XP_853524 248 28120 S238 A I Q G P E D S P S R Q S R R
Cat Felis silvestris
Mouse Mus musculus Q99KX1 247 28037 S237 A I Q G P E D S P S R Q S R R
Rat Rattus norvegicus NP_001101150 282 32202 S255 R E K I H R N S T I E S G R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518073 270 29614 S260 A I Q G P E D S P S R Q S R R
Chicken Gallus gallus NP_001025947 242 27468 S232 A I Q G P E D S P S R Q S R R
Frog Xenopus laevis NP_001085349 242 27458 N232 A I Q G P E D N T A R P S R R
Zebra Danio Brachydanio rerio NP_001020687 250 28397 S226 A L T A P P T S S S S P S P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NKV0 376 41359 A344 S I H P H P Y A A N P R R Q Q
Honey Bee Apis mellifera XP_393366 257 29409 S232 D P S G R W T S S P R R S L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796343 284 31913 G274 P T P A R P Q G P S R G G R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 34.7 97.9 N.A. 96.7 34.4 N.A. 75.5 84.2 66.9 58 N.A. 26.3 32.6 N.A. 39.4
Protein Similarity: 100 55.4 55.3 98.7 N.A. 97.5 52.1 N.A. 80.7 89.5 81 72.8 N.A. 38.8 50.1 N.A. 56.3
P-Site Identity: 100 26.6 26.6 100 N.A. 100 20 N.A. 100 100 73.3 40 N.A. 6.6 33.3 N.A. 26.6
P-Site Similarity: 100 53.3 53.3 100 N.A. 100 33.3 N.A. 100 100 86.6 46.6 N.A. 46.6 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 0 0 16 0 0 0 8 8 24 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 47 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 16 0 0 47 0 0 0 0 8 16 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 54 0 0 0 8 0 0 0 8 16 16 0 % G
% His: 0 0 8 0 16 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 54 0 8 0 0 0 0 0 8 16 0 0 0 0 % I
% Lys: 0 0 8 16 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 8 0 8 0 0 0 0 0 % N
% Pro: 8 8 8 8 70 24 0 0 62 8 8 16 0 8 0 % P
% Gln: 0 0 47 0 0 16 24 0 0 0 0 39 0 8 16 % Q
% Arg: 24 16 0 0 16 8 0 0 0 0 62 16 16 62 85 % R
% Ser: 8 0 8 0 0 0 0 77 16 54 8 8 62 0 0 % S
% Thr: 0 8 8 0 0 0 16 0 16 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _