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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF2
All Species:
22.12
Human Site:
S240
Identified Species:
40.56
UniProt:
Q15773
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15773
NP_005430.1
248
28147
S240
Q
G
P
E
D
S
P
S
R
Q
S
R
R
Y
D
Chimpanzee
Pan troglodytes
XP_001154028
283
32140
A257
E
K
P
Q
Q
S
P
A
I
E
H
G
R
R
S
Rhesus Macaque
Macaca mulatta
XP_001101964
282
32058
A256
E
K
P
Q
Q
S
P
A
I
E
R
G
R
R
S
Dog
Lupus familis
XP_853524
248
28120
S240
Q
G
P
E
D
S
P
S
R
Q
S
R
R
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99KX1
247
28037
S239
Q
G
P
E
D
S
P
S
R
Q
S
R
R
Y
D
Rat
Rattus norvegicus
NP_001101150
282
32202
I257
K
I
H
R
N
S
T
I
E
S
G
R
R
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518073
270
29614
S262
Q
G
P
E
D
S
P
S
R
Q
S
R
R
Y
D
Chicken
Gallus gallus
NP_001025947
242
27468
S234
Q
G
P
E
D
S
P
S
R
Q
S
R
R
Y
D
Frog
Xenopus laevis
NP_001085349
242
27458
A234
Q
G
P
E
D
N
T
A
R
P
S
R
R
Y
D
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
S228
T
A
P
P
T
S
S
S
S
P
S
P
R
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
N346
H
P
H
P
Y
A
A
N
P
R
R
Q
Q
R
A
Honey Bee
Apis mellifera
XP_393366
257
29409
P234
S
G
R
W
T
S
S
P
R
R
S
L
R
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
S276
P
A
R
P
Q
G
P
S
R
G
G
R
Q
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
34.7
97.9
N.A.
96.7
34.4
N.A.
75.5
84.2
66.9
58
N.A.
26.3
32.6
N.A.
39.4
Protein Similarity:
100
55.4
55.3
98.7
N.A.
97.5
52.1
N.A.
80.7
89.5
81
72.8
N.A.
38.8
50.1
N.A.
56.3
P-Site Identity:
100
26.6
26.6
100
N.A.
100
20
N.A.
100
100
73.3
33.3
N.A.
0
33.3
N.A.
33.3
P-Site Similarity:
100
53.3
53.3
100
N.A.
100
40
N.A.
100
100
86.6
46.6
N.A.
33.3
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
8
8
24
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
54
% D
% Glu:
16
0
0
47
0
0
0
0
8
16
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
54
0
0
0
8
0
0
0
8
16
16
0
0
0
% G
% His:
8
0
16
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
8
16
0
0
0
0
0
0
% I
% Lys:
8
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
8
70
24
0
0
62
8
8
16
0
8
0
0
0
% P
% Gln:
47
0
0
16
24
0
0
0
0
39
0
8
16
0
0
% Q
% Arg:
0
0
16
8
0
0
0
0
62
16
16
62
85
31
0
% R
% Ser:
8
0
0
0
0
77
16
54
8
8
62
0
0
0
24
% S
% Thr:
8
0
0
0
16
0
16
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _