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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLF2 All Species: 18.48
Human Site: S32 Identified Species: 33.89
UniProt: Q15773 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15773 NP_005430.1 248 28147 S32 Q H M S R M L S G G F G Y S P
Chimpanzee Pan troglodytes XP_001154028 283 32140 M30 R E N M R Q M M R S F S E P F
Rhesus Macaque Macaca mulatta XP_001101964 282 32058 R31 E N M P Q M M R S L S E P F G
Dog Lupus familis XP_853524 248 28120 S32 Q H M N R M L S G G F G Y S P
Cat Felis silvestris
Mouse Mus musculus Q99KX1 247 28037 S32 Q H M S R M L S G G F G Y S P
Rat Rattus norvegicus NP_001101150 282 32202 M30 R E S M R N M M R S F S E P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518073 270 29614 S56 X X X X X X L S G G L G Y S P
Chicken Gallus gallus NP_001025947 242 27468 S32 Q H M N R M L S G S F G F G P
Frog Xenopus laevis NP_001085349 242 27458 S33 Q H M R H M F S G D Y G M S P
Zebra Danio Brachydanio rerio NP_001020687 250 28397 M25 F A A H R H Q M R S M F G S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NKV0 376 41359 D13 A L M G D F D D D L G L M N N
Honey Bee Apis mellifera XP_393366 257 29409 N32 R H M N N M M N S L F N D P F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796343 284 31913 M31 R H M V P M A M G S M F P Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 34.7 97.9 N.A. 96.7 34.4 N.A. 75.5 84.2 66.9 58 N.A. 26.3 32.6 N.A. 39.4
Protein Similarity: 100 55.4 55.3 98.7 N.A. 97.5 52.1 N.A. 80.7 89.5 81 72.8 N.A. 38.8 50.1 N.A. 56.3
P-Site Identity: 100 13.3 13.3 93.3 N.A. 100 13.3 N.A. 53.3 73.3 60 13.3 N.A. 6.6 26.6 N.A. 26.6
P-Site Similarity: 100 26.6 40 100 N.A. 100 26.6 N.A. 53.3 86.6 66.6 13.3 N.A. 13.3 53.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 8 8 8 0 0 8 0 0 % D
% Glu: 8 16 0 0 0 0 0 0 0 0 0 8 16 0 0 % E
% Phe: 8 0 0 0 0 8 8 0 0 0 54 16 8 8 24 % F
% Gly: 0 0 0 8 0 0 0 0 54 31 8 47 8 8 8 % G
% His: 0 54 0 8 8 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 0 0 39 0 0 24 8 8 0 0 8 % L
% Met: 0 0 70 16 0 62 31 31 0 0 16 0 16 0 0 % M
% Asn: 0 8 8 24 8 8 0 8 0 0 0 8 0 8 8 % N
% Pro: 0 0 0 8 8 0 0 0 0 0 0 0 16 24 47 % P
% Gln: 39 0 0 0 8 8 8 0 0 0 0 0 0 8 8 % Q
% Arg: 31 0 0 8 54 0 0 8 24 0 0 0 0 0 0 % R
% Ser: 0 0 8 16 0 0 0 47 16 39 8 16 0 47 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 31 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _