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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLF2 All Species: 9.39
Human Site: S55 Identified Species: 17.22
UniProt: Q15773 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15773 NP_005430.1 248 28147 S55 M P G T R P A S R R M Q Q A G
Chimpanzee Pan troglodytes XP_001154028 283 32140 N53 D G R G R A H N R R G H N D G
Rhesus Macaque Macaca mulatta XP_001101964 282 32058 H54 G R G R A R N H R G H N D E D
Dog Lupus familis XP_853524 248 28120 S55 M P G A R P A S R R M Q Q A G
Cat Felis silvestris
Mouse Mus musculus Q99KX1 247 28037 S55 M P A T R P A S R R M Q A G A
Rat Rattus norvegicus NP_001101150 282 32202 N53 D G R G R T H N R R E R D D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518073 270 29614 G79 V P G A R P A G R R I Q A G A
Chicken Gallus gallus NP_001025947 242 27468 G55 T P G A R Q A G R R M R A G A
Frog Xenopus laevis NP_001085349 242 27458 A56 V R G L P R P A P S H T I Q P
Zebra Danio Brachydanio rerio NP_001020687 250 28397 T48 P Q I Q H P R T R I Q P Q A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NKV0 376 41359 M36 M N M Q M R S M N R L M N S F
Honey Bee Apis mellifera XP_393366 257 29409 H55 N A I A H A N H R N R N H Q D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796343 284 31913 P54 G V R R P P Q P F R P N P A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 34.7 97.9 N.A. 96.7 34.4 N.A. 75.5 84.2 66.9 58 N.A. 26.3 32.6 N.A. 39.4
Protein Similarity: 100 55.4 55.3 98.7 N.A. 97.5 52.1 N.A. 80.7 89.5 81 72.8 N.A. 38.8 50.1 N.A. 56.3
P-Site Identity: 100 26.6 13.3 93.3 N.A. 73.3 26.6 N.A. 53.3 46.6 6.6 33.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 33.3 13.3 93.3 N.A. 73.3 40 N.A. 66.6 53.3 20 40 N.A. 33.3 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 31 8 16 39 8 0 0 0 0 24 31 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 0 0 0 0 0 0 16 16 16 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 16 16 47 16 0 0 0 16 0 8 8 0 0 24 39 % G
% His: 0 0 0 0 16 0 16 16 0 0 16 8 8 0 0 % H
% Ile: 0 0 16 0 0 0 0 0 0 8 8 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % L
% Met: 31 0 8 0 8 0 0 8 0 0 31 8 0 0 0 % M
% Asn: 8 8 0 0 0 0 16 16 8 8 0 24 16 0 8 % N
% Pro: 8 39 0 0 16 47 8 8 8 0 8 8 8 0 8 % P
% Gln: 0 8 0 16 0 8 8 0 0 0 8 31 24 16 0 % Q
% Arg: 0 16 24 16 54 24 8 0 77 70 8 16 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 24 0 8 0 0 0 8 0 % S
% Thr: 8 0 0 16 0 8 0 8 0 0 0 8 0 0 0 % T
% Val: 16 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _