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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLF2 All Species: 47.88
Human Site: T137 Identified Species: 87.78
UniProt: Q15773 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15773 NP_005430.1 248 28147 T137 A P G G I R E T R R T V R D S
Chimpanzee Pan troglodytes XP_001154028 283 32140 T155 A P G G I K E T R K A M R D S
Rhesus Macaque Macaca mulatta XP_001101964 282 32058 T154 A P G G I K E T R K A M R D S
Dog Lupus familis XP_853524 248 28120 T137 A P G G I R E T R R T V R D S
Cat Felis silvestris
Mouse Mus musculus Q99KX1 247 28037 T136 A P G G I R E T R R T V R D S
Rat Rattus norvegicus NP_001101150 282 32202 T155 A P G G V K E T R K A I R D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518073 270 29614 T159 A P G G I R E T R R T V R D S
Chicken Gallus gallus NP_001025947 242 27468 T135 A P G G I R E T R R T V R D S
Frog Xenopus laevis NP_001085349 242 27458 M132 H E T T Q T R M A P G G I R E
Zebra Danio Brachydanio rerio NP_001020687 250 28397 T130 A P G G I R E T R Q T M R D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NKV0 376 41359 T137 G P G G V R E T R R T V Q D S
Honey Bee Apis mellifera XP_393366 257 29409 T131 V P G G I K E T K T T V C D S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796343 284 31913 T140 A P G G I R E T R K T V R D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 34.7 97.9 N.A. 96.7 34.4 N.A. 75.5 84.2 66.9 58 N.A. 26.3 32.6 N.A. 39.4
Protein Similarity: 100 55.4 55.3 98.7 N.A. 97.5 52.1 N.A. 80.7 89.5 81 72.8 N.A. 38.8 50.1 N.A. 56.3
P-Site Identity: 100 73.3 73.3 100 N.A. 100 66.6 N.A. 100 100 0 86.6 N.A. 80 66.6 N.A. 93.3
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 93.3 N.A. 100 100 0 100 N.A. 93.3 80 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 77 0 0 0 0 0 0 0 8 0 24 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % D
% Glu: 0 8 0 0 0 0 93 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 93 93 0 0 0 0 0 0 8 8 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 77 0 0 0 0 0 0 8 8 0 0 % I
% Lys: 0 0 0 0 0 31 0 0 8 31 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 24 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 93 0 0 0 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 62 8 0 85 47 0 0 77 8 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93 % S
% Thr: 0 0 8 8 0 8 0 93 0 8 70 0 0 0 0 % T
% Val: 8 0 0 0 16 0 0 0 0 0 0 62 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _