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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLF2 All Species: 4.24
Human Site: T51 Identified Species: 7.78
UniProt: Q15773 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15773 NP_005430.1 248 28147 T51 T D G N M P G T R P A S R R M
Chimpanzee Pan troglodytes XP_001154028 283 32140 G49 L S I S D G R G R A H N R R G
Rhesus Macaque Macaca mulatta XP_001101964 282 32058 R50 S I P D G R G R A R N H R G H
Dog Lupus familis XP_853524 248 28120 A51 T D G N M P G A R P A S R R M
Cat Felis silvestris
Mouse Mus musculus Q99KX1 247 28037 T51 T D G N M P A T R P A S R R M
Rat Rattus norvegicus NP_001101150 282 32202 G49 L S I S D G R G R T H N R R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518073 270 29614 A75 T D G T V P G A R P A G R R I
Chicken Gallus gallus NP_001025947 242 27468 A51 T D G T T P G A R Q A G R R M
Frog Xenopus laevis NP_001085349 242 27458 L52 T D G S V R G L P R P A P S H
Zebra Danio Brachydanio rerio NP_001020687 250 28397 Q44 F A L T P Q I Q H P R T R I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NKV0 376 41359 Q32 T M N A M N M Q M R S M N R L
Honey Bee Apis mellifera XP_393366 257 29409 A51 H P S H N A I A H A N H R N R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796343 284 31913 R50 I E A R G V R R P P Q P F R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 34.7 97.9 N.A. 96.7 34.4 N.A. 75.5 84.2 66.9 58 N.A. 26.3 32.6 N.A. 39.4
Protein Similarity: 100 55.4 55.3 98.7 N.A. 97.5 52.1 N.A. 80.7 89.5 81 72.8 N.A. 38.8 50.1 N.A. 56.3
P-Site Identity: 100 20 13.3 93.3 N.A. 93.3 20 N.A. 66.6 66.6 26.6 13.3 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 33.3 26.6 93.3 N.A. 93.3 33.3 N.A. 80 66.6 46.6 20 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 0 8 8 31 8 16 39 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 47 0 8 16 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 47 0 16 16 47 16 0 0 0 16 0 8 8 % G
% His: 8 0 0 8 0 0 0 0 16 0 16 16 0 0 16 % H
% Ile: 8 8 16 0 0 0 16 0 0 0 0 0 0 8 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 0 8 0 0 0 0 8 0 0 0 0 0 0 8 % L
% Met: 0 8 0 0 31 0 8 0 8 0 0 8 0 0 31 % M
% Asn: 0 0 8 24 8 8 0 0 0 0 16 16 8 8 0 % N
% Pro: 0 8 8 0 8 39 0 0 16 47 8 8 8 0 8 % P
% Gln: 0 0 0 0 0 8 0 16 0 8 8 0 0 0 8 % Q
% Arg: 0 0 0 8 0 16 24 16 54 24 8 0 77 70 8 % R
% Ser: 8 16 8 24 0 0 0 0 0 0 8 24 0 8 0 % S
% Thr: 54 0 0 24 8 0 0 16 0 8 0 8 0 0 0 % T
% Val: 0 0 0 0 16 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _