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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF2
All Species:
18.18
Human Site:
Y181
Identified Species:
33.33
UniProt:
Q15773
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15773
NP_005430.1
248
28147
Y181
D
Q
E
E
R
Q
D
Y
I
N
L
D
E
S
E
Chimpanzee
Pan troglodytes
XP_001154028
283
32140
F199
D
E
E
V
N
Q
E
F
I
N
M
N
E
S
D
Rhesus Macaque
Macaca mulatta
XP_001101964
282
32058
F198
D
E
E
V
N
Q
E
F
I
N
M
N
E
N
D
Dog
Lupus familis
XP_853524
248
28120
Y181
D
Q
E
E
R
Q
D
Y
I
N
L
D
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99KX1
247
28037
Y180
D
Q
E
E
R
Q
D
Y
I
N
L
D
E
S
E
Rat
Rattus norvegicus
NP_001101150
282
32202
F199
D
E
E
V
D
Q
E
F
I
N
M
N
E
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518073
270
29614
Y203
D
Q
E
E
R
Q
D
Y
I
N
L
D
E
S
D
Chicken
Gallus gallus
NP_001025947
242
27468
Y179
D
Q
E
E
R
Q
D
Y
I
N
M
D
E
S
D
Frog
Xenopus laevis
NP_001085349
242
27458
G176
R
S
H
N
R
R
T
G
D
Q
E
E
R
Q
E
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
F174
D
R
E
E
R
Q
D
F
F
N
L
E
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
F181
Q
L
E
E
R
Q
E
F
I
N
L
E
E
G
E
Honey Bee
Apis mellifera
XP_393366
257
29409
F175
E
Q
E
E
H
Q
E
F
I
N
L
D
E
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
F184
D
Q
E
E
K
Q
D
F
L
N
I
D
E
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
34.7
97.9
N.A.
96.7
34.4
N.A.
75.5
84.2
66.9
58
N.A.
26.3
32.6
N.A.
39.4
Protein Similarity:
100
55.4
55.3
98.7
N.A.
97.5
52.1
N.A.
80.7
89.5
81
72.8
N.A.
38.8
50.1
N.A.
56.3
P-Site Identity:
100
46.6
40
100
N.A.
100
46.6
N.A.
93.3
86.6
13.3
73.3
N.A.
60
66.6
N.A.
66.6
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
86.6
N.A.
100
100
26.6
93.3
N.A.
80
86.6
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
0
0
0
8
0
54
0
8
0
0
54
0
0
47
% D
% Glu:
8
24
93
70
0
0
39
0
0
0
8
24
93
8
54
% E
% Phe:
0
0
0
0
0
0
0
54
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
77
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
8
0
54
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% M
% Asn:
0
0
0
8
16
0
0
0
0
93
0
24
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
54
0
0
0
93
0
0
0
8
0
0
0
8
0
% Q
% Arg:
8
8
0
0
62
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
0
0
0
70
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _