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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPED2
All Species:
21.52
Human Site:
T272
Identified Species:
43.03
UniProt:
Q15777
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15777
NP_001575.1
294
33360
T272
T
T
Y
I
N
A
S
T
C
T
V
S
F
Q
P
Chimpanzee
Pan troglodytes
XP_508348
262
29971
R241
E
L
L
N
T
V
Q
R
R
V
R
P
K
L
H
Rhesus Macaque
Macaca mulatta
XP_001086848
277
31508
V256
V
F
G
G
I
H
E
V
N
P
V
S
I
S
K
Dog
Lupus familis
XP_851809
398
44525
V376
T
T
Y
V
N
A
S
V
C
T
V
N
Y
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZJ0
294
33355
T272
T
T
Y
I
N
A
S
T
C
T
V
S
F
Q
P
Rat
Rattus norvegicus
B1WBP0
294
33317
T272
T
T
Y
I
N
A
S
T
C
T
V
S
F
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517333
187
21511
N166
N
V
Q
S
L
L
T
N
C
I
Y
L
Q
D
S
Chicken
Gallus gallus
XP_419641
294
33328
T272
T
T
Y
I
N
A
S
T
C
T
V
S
F
Q
P
Frog
Xenopus laevis
NP_001086221
294
33372
T272
T
T
Y
V
N
A
S
T
C
T
V
S
F
Q
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394142
298
33177
T273
I
I
Y
V
N
A
S
T
C
D
L
N
Y
L
P
Nematode Worm
Caenorhab. elegans
Q22306
396
44850
M355
T
K
F
I
N
C
C
M
C
N
E
N
L
D
L
Sea Urchin
Strong. purpuratus
XP_001202740
207
23687
N186
D
V
H
Y
R
P
C
N
P
P
I
V
F
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
88.7
60.5
N.A.
99.6
99.3
N.A.
49.3
99.6
97.2
N.A.
N.A.
N.A.
46.9
35.6
39.8
Protein Similarity:
100
88.7
91.1
68.5
N.A.
100
99.3
N.A.
56.1
99.6
98.9
N.A.
N.A.
N.A.
62.7
47.9
52
P-Site Identity:
100
0
13.3
73.3
N.A.
100
100
N.A.
6.6
100
93.3
N.A.
N.A.
N.A.
46.6
26.6
6.6
P-Site Similarity:
100
0
13.3
93.3
N.A.
100
100
N.A.
13.3
100
100
N.A.
N.A.
N.A.
73.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
17
0
75
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
9
0
0
0
25
0
% D
% Glu:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
0
0
0
0
50
0
0
% F
% Gly:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
9
0
42
9
0
0
0
0
9
9
0
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% K
% Leu:
0
9
9
0
9
9
0
0
0
0
9
9
9
17
17
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
67
0
0
17
9
9
0
25
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
9
17
0
9
0
0
59
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
9
50
0
% Q
% Arg:
0
0
0
0
9
0
0
9
9
0
9
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
59
0
0
0
0
50
0
9
9
% S
% Thr:
59
50
0
0
9
0
9
50
0
50
0
0
0
0
0
% T
% Val:
9
17
0
25
0
9
0
17
0
9
59
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
59
9
0
0
0
0
0
0
9
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _