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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPED2
All Species:
26.06
Human Site:
Y135
Identified Species:
52.12
UniProt:
Q15777
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15777
NP_001575.1
294
33360
Y135
A
D
L
V
K
Q
D
Y
Y
R
F
P
S
V
S
Chimpanzee
Pan troglodytes
XP_508348
262
29971
T121
I
A
G
N
H
E
L
T
F
D
K
E
F
M
A
Rhesus Macaque
Macaca mulatta
XP_001086848
277
31508
Y135
A
D
L
V
K
Q
D
Y
Y
R
F
P
S
V
S
Dog
Lupus familis
XP_851809
398
44525
F239
A
D
L
I
K
Q
D
F
Y
Y
F
P
S
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZJ0
294
33355
Y135
A
D
L
V
K
Q
D
Y
Y
R
F
P
S
V
S
Rat
Rattus norvegicus
B1WBP0
294
33317
Y135
A
D
L
V
K
Q
D
Y
Y
R
F
P
S
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517333
187
21511
P46
I
N
Q
G
R
F
Q
P
P
H
V
Q
M
V
D
Chicken
Gallus gallus
XP_419641
294
33328
Y135
A
D
L
V
K
Q
D
Y
Y
R
F
P
S
V
S
Frog
Xenopus laevis
NP_001086221
294
33372
Y135
A
D
L
V
K
Q
D
Y
Y
R
F
P
S
V
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394142
298
33177
T137
S
I
L
D
N
I
P
T
L
G
M
S
K
D
T
Nematode Worm
Caenorhab. elegans
Q22306
396
44850
P213
K
L
K
Q
E
S
E
P
K
E
M
A
L
K
Q
Sea Urchin
Strong. purpuratus
XP_001202740
207
23687
T66
R
S
L
L
T
N
C
T
Y
L
E
D
S
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
88.7
60.5
N.A.
99.6
99.3
N.A.
49.3
99.6
97.2
N.A.
N.A.
N.A.
46.9
35.6
39.8
Protein Similarity:
100
88.7
91.1
68.5
N.A.
100
99.3
N.A.
56.1
99.6
98.9
N.A.
N.A.
N.A.
62.7
47.9
52
P-Site Identity:
100
0
100
80
N.A.
100
100
N.A.
6.6
100
100
N.A.
N.A.
N.A.
6.6
0
20
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
100
N.A.
20
100
100
N.A.
N.A.
N.A.
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
0
9
0
0
59
0
0
9
0
9
0
9
9
% D
% Glu:
0
0
0
0
9
9
9
0
0
9
9
9
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
9
9
0
59
0
9
0
0
% F
% Gly:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
17
9
0
9
0
9
0
0
0
0
0
0
0
0
9
% I
% Lys:
9
0
9
0
59
0
0
0
9
0
9
0
9
9
0
% K
% Leu:
0
9
75
9
0
0
9
0
9
9
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
9
9
0
% M
% Asn:
0
9
0
9
9
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
17
9
0
0
59
0
0
0
% P
% Gln:
0
0
9
9
0
59
9
0
0
0
0
9
0
0
9
% Q
% Arg:
9
0
0
0
9
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
9
9
0
0
0
9
0
0
0
0
0
9
67
0
59
% S
% Thr:
0
0
0
0
9
0
0
25
0
0
0
0
0
0
9
% T
% Val:
0
0
0
50
0
0
0
0
0
0
9
0
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
67
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _