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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPED2
All Species:
29.39
Human Site:
Y257
Identified Species:
58.79
UniProt:
Q15777
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15777
NP_001575.1
294
33360
Y257
F
G
G
I
H
E
G
Y
G
I
M
T
D
G
Y
Chimpanzee
Pan troglodytes
XP_508348
262
29971
E226
F
R
D
W
V
P
K
E
L
Q
R
V
G
C
V
Rhesus Macaque
Macaca mulatta
XP_001086848
277
31508
R241
E
L
L
N
T
V
Q
R
R
V
R
P
K
L
H
Dog
Lupus familis
XP_851809
398
44525
Y361
F
G
H
I
H
E
G
Y
G
V
M
A
D
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZJ0
294
33355
Y257
F
G
G
I
H
E
G
Y
G
I
M
T
D
G
Y
Rat
Rattus norvegicus
B1WBP0
294
33317
Y257
F
G
G
I
H
E
G
Y
G
T
M
T
D
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517333
187
21511
K151
Y
Y
F
P
S
V
S
K
L
K
P
E
N
Y
E
Chicken
Gallus gallus
XP_419641
294
33328
Y257
F
G
G
I
H
E
G
Y
G
I
M
T
D
G
Y
Frog
Xenopus laevis
NP_001086221
294
33372
Y257
F
G
G
I
H
E
G
Y
G
I
M
T
D
G
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394142
298
33177
Y258
F
G
H
I
H
E
G
Y
G
I
S
T
D
G
K
Nematode Worm
Caenorhab. elegans
Q22306
396
44850
Y340
F
G
H
I
H
E
G
Y
G
C
T
T
D
G
Y
Sea Urchin
Strong. purpuratus
XP_001202740
207
23687
T171
V
T
T
D
G
Q
T
T
F
V
N
A
A
I
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
88.7
60.5
N.A.
99.6
99.3
N.A.
49.3
99.6
97.2
N.A.
N.A.
N.A.
46.9
35.6
39.8
Protein Similarity:
100
88.7
91.1
68.5
N.A.
100
99.3
N.A.
56.1
99.6
98.9
N.A.
N.A.
N.A.
62.7
47.9
52
P-Site Identity:
100
6.6
0
73.3
N.A.
100
93.3
N.A.
0
100
100
N.A.
N.A.
N.A.
80
80
0
P-Site Similarity:
100
6.6
13.3
80
N.A.
100
93.3
N.A.
13.3
100
100
N.A.
N.A.
N.A.
80
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% C
% Asp:
0
0
9
9
0
0
0
0
0
0
0
0
67
0
0
% D
% Glu:
9
0
0
0
0
67
0
9
0
0
0
9
0
0
9
% E
% Phe:
75
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
67
42
0
9
0
67
0
67
0
0
0
9
67
0
% G
% His:
0
0
25
0
67
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
67
0
0
0
0
0
42
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
9
9
0
9
0
0
9
0
9
% K
% Leu:
0
9
9
0
0
0
0
0
17
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
0
0
0
9
0
9
0
0
0
0
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
9
0
17
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% S
% Thr:
0
9
9
0
9
0
9
9
0
9
9
59
0
0
9
% T
% Val:
9
0
0
0
9
17
0
0
0
25
0
9
0
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
67
0
0
0
0
0
9
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _