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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCOA1 All Species: 10.3
Human Site: T499 Identified Species: 28.33
UniProt: Q15788 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15788 NP_003734.3 1441 156757 T499 Q V T S G L A T R P R M P N N
Chimpanzee Pan troglodytes XP_001145713 1441 156756 T499 Q V T S G L A T R P R M P N N
Rhesus Macaque Macaca mulatta XP_001082161 1464 159057 L552 G V S L G S S L A S P D L K M
Dog Lupus familis XP_532891 1247 135615 T371 L S S P V S M T G T A C N N S
Cat Felis silvestris
Mouse Mus musculus P70365 1447 156997 T500 Q A N S G L A T R A R M S N N
Rat Rattus norvegicus Q9WUI9 1465 159417 L552 G V S L G P S L A S P D L K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8QGQ6 875 98641
Frog Xenopus laevis Q9W705 1516 166138 S542 G P L A P P L S S P D L K G G
Zebra Danio Brachydanio rerio Q98TW1 1505 161775 M508 S L H S P A S M C T S S T G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 32.1 82 N.A. 92.5 31.6 N.A. N.A. 21.1 30.1 31.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 48.7 84.5 N.A. 96.2 48.4 N.A. N.A. 33.3 45.9 45.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 13.3 N.A. 73.3 13.3 N.A. N.A. 0 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 26.6 N.A. 73.3 26.6 N.A. N.A. 0 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 12 34 0 23 12 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 12 23 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 0 0 0 56 0 0 0 12 0 0 0 0 23 23 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 12 23 0 % K
% Leu: 12 12 12 23 0 34 12 23 0 0 0 12 23 0 0 % L
% Met: 0 0 0 0 0 0 12 12 0 0 0 34 0 0 23 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 12 45 34 % N
% Pro: 0 12 0 12 23 23 0 0 0 34 23 0 23 0 0 % P
% Gln: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 34 0 34 0 0 0 0 % R
% Ser: 12 12 34 45 0 23 34 12 12 23 12 12 12 0 12 % S
% Thr: 0 0 23 0 0 0 0 45 0 23 0 0 12 0 0 % T
% Val: 0 45 0 0 12 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _