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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMAD1 All Species: 28.79
Human Site: T202 Identified Species: 63.33
UniProt: Q15797 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15797 NP_001003688.1 465 52260 T202 S P G S S S S T Y P H S P T S
Chimpanzee Pan troglodytes XP_001148109 465 52214 T202 S P G S S S S T Y P H S P T S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532681 465 52174 T202 S P G S S S G T Y P H S P T S
Cat Felis silvestris
Mouse Mus musculus P70340 465 52100 T202 S P G G S S S T Y P H S P T S
Rat Rattus norvegicus P97588 468 52695 H205 S S S S T Y P H S P T S S D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510186 465 52277 T202 S P G S S S S T Y P H S P T S
Chicken Gallus gallus Q56I99 465 52210 Y202 P S P A S S T Y P S S P A S S
Frog Xenopus laevis NP_001079973 464 52355 T201 N S P G S S S T Y P H S P A S
Zebra Danio Brachydanio rerio Q9I8V2 472 53048 T209 S G T G S T A T F P H S P S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42003 455 50486 S192 N S G F N S H S L S T S N T S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q02330 418 47907 M162 A K F Q L M E M S G S R M P Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 99.3 N.A. 98.7 97.4 N.A. 98.9 90.3 95.6 88.5 N.A. 75 N.A. 51.6 N.A.
Protein Similarity: 100 100 N.A. 99.5 N.A. 99.3 97.8 N.A. 99.3 92.4 97.4 93.8 N.A. 83.6 N.A. 63.8 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 26.6 N.A. 100 20 66.6 53.3 N.A. 33.3 N.A. 0 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 33.3 N.A. 100 40 73.3 80 N.A. 53.3 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 10 0 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 55 28 0 0 10 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 10 0 0 64 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 10 0 0 0 0 10 0 0 % M
% Asn: 19 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 10 46 19 0 0 0 10 0 10 73 0 10 64 10 10 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 64 37 10 46 73 73 46 10 19 19 19 82 10 19 82 % S
% Thr: 0 0 10 0 10 10 10 64 0 0 19 0 0 55 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 10 55 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _