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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCE
All Species:
28.79
Human Site:
S124
Identified Species:
48.72
UniProt:
Q15813
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15813
NP_001072983.1
527
59346
S124
D
S
I
M
K
Q
Q
S
Q
L
S
K
L
Q
E
Chimpanzee
Pan troglodytes
XP_001154821
527
59309
S124
D
S
I
M
K
Q
Q
S
Q
L
S
K
L
Q
E
Rhesus Macaque
Macaca mulatta
XP_001100733
527
59584
S124
D
S
L
M
K
Q
Q
S
Q
L
S
K
L
Q
E
Dog
Lupus familis
XP_536339
528
59149
S124
D
S
I
I
K
Q
Q
S
Q
L
S
K
L
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIV8
524
59067
S124
E
H
I
T
K
K
Q
S
Q
L
R
A
L
Q
D
Rat
Rattus norvegicus
Q5FVQ9
524
59024
S124
E
H
I
T
K
K
Q
S
Q
L
R
S
L
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512384
490
54035
R109
Q
A
L
V
I
G
N
R
P
V
E
T
V
G
F
Chicken
Gallus gallus
XP_423980
529
59195
S125
D
S
I
E
K
K
Q
S
Q
L
H
R
L
V
H
Frog
Xenopus laevis
Q5U508
522
58770
L124
E
Q
S
K
L
N
K
L
K
D
V
S
L
R
E
Zebra Danio
Brachydanio rerio
Q5U378
521
59024
T123
K
Q
S
V
K
N
L
T
E
V
G
L
R
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995747
523
59405
S131
D
K
I
A
R
K
Q
S
K
F
E
Q
L
E
E
Honey Bee
Apis mellifera
XP_001120710
465
53741
D93
I
R
Y
G
F
I
N
D
E
L
A
G
I
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782736
426
47879
G53
P
E
R
G
K
H
D
G
S
H
N
G
T
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39937
518
59239
K119
D
E
L
N
A
R
N
K
N
Y
K
K
L
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.3
81.2
N.A.
74.5
75.3
N.A.
54.6
62.1
57.8
52.1
N.A.
31.8
34.5
N.A.
33
Protein Similarity:
100
99.6
96.3
89.9
N.A.
85.3
85.1
N.A.
65.8
74.4
72.3
68.6
N.A.
53.1
53.3
N.A.
49.1
P-Site Identity:
100
100
93.3
86.6
N.A.
53.3
53.3
N.A.
0
60
13.3
6.6
N.A.
40
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
73.3
73.3
N.A.
33.3
73.3
40
40
N.A.
73.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
50
0
0
0
0
0
8
8
0
8
0
0
0
8
22
% D
% Glu:
22
15
0
8
0
0
0
0
15
0
15
0
0
8
36
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
15
0
8
0
8
0
0
8
15
0
8
0
% G
% His:
0
15
0
0
0
8
0
0
0
8
8
0
0
0
8
% H
% Ile:
8
0
50
8
8
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
8
0
8
65
29
8
8
15
0
8
36
0
0
8
% K
% Leu:
0
0
22
0
8
0
8
8
0
58
0
8
72
0
0
% L
% Met:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
15
22
0
8
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
15
0
0
0
29
58
0
50
0
0
8
0
50
0
% Q
% Arg:
0
8
8
0
8
8
0
8
0
0
15
8
8
22
8
% R
% Ser:
0
36
15
0
0
0
0
58
8
0
29
15
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
8
0
0
0
8
8
0
0
% T
% Val:
0
0
0
15
0
0
0
0
0
15
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _