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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCE All Species: 30
Human Site: S291 Identified Species: 50.77
UniProt: Q15813 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15813 NP_001072983.1 527 59346 S291 L S D T G I S S L H F P D A G
Chimpanzee Pan troglodytes XP_001154821 527 59309 S291 L S D T G I S S L H F P D A G
Rhesus Macaque Macaca mulatta XP_001100733 527 59584 S291 L S D I G I S S I H F P D A G
Dog Lupus familis XP_536339 528 59149 S292 L S D V G I S S I H F P D A V
Cat Felis silvestris
Mouse Mus musculus Q8CIV8 524 59067 S292 L S D I G L S S I H F P D A E
Rat Rattus norvegicus Q5FVQ9 524 59024 S292 L S D I G L S S I H F P D A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512384 490 54035 S262 T L R L L D L S G N P L V D E
Chicken Gallus gallus XP_423980 529 59195 S293 L T N N G I S S V H F P D A E
Frog Xenopus laevis Q5U508 522 58770 S287 V S N N I I S S I S F P D V D
Zebra Danio Brachydanio rerio Q5U378 521 59024 E284 L S S T S L S E I K F S D V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995747 523 59405 E300 I M E N G I E E I K L P D C D
Honey Bee Apis mellifera XP_001120710 465 53741 T246 T T E P I V K T T A F F N L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782736 426 47879 A206 S L C S A F C A L E Q L F L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39937 518 59239 I288 L N V S N N Q I S R A P S I A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 93.3 81.2 N.A. 74.5 75.3 N.A. 54.6 62.1 57.8 52.1 N.A. 31.8 34.5 N.A. 33
Protein Similarity: 100 99.6 96.3 89.9 N.A. 85.3 85.1 N.A. 65.8 74.4 72.3 68.6 N.A. 53.1 53.3 N.A. 49.1
P-Site Identity: 100 100 86.6 80 N.A. 73.3 73.3 N.A. 6.6 66.6 46.6 40 N.A. 26.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 13.3 86.6 66.6 53.3 N.A. 46.6 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 0 8 8 0 0 50 8 % A
% Cys: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 43 0 0 8 0 0 0 0 0 0 72 8 15 % D
% Glu: 0 0 15 0 0 0 8 15 0 8 0 0 0 0 29 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 72 8 8 0 0 % F
% Gly: 0 0 0 0 58 0 0 0 8 0 0 0 0 0 22 % G
% His: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % H
% Ile: 8 0 0 22 15 50 0 8 50 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 15 0 0 0 0 0 % K
% Leu: 65 15 0 8 8 22 8 0 22 0 8 15 0 15 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 15 22 8 8 0 0 0 8 0 0 8 0 8 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 8 72 0 0 8 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 8 % R
% Ser: 8 58 8 15 8 0 65 65 8 8 0 8 8 0 0 % S
% Thr: 15 15 0 22 0 0 0 8 8 0 0 0 0 0 0 % T
% Val: 8 0 8 8 0 8 0 0 8 0 0 0 8 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _