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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCE All Species: 40.3
Human Site: S516 Identified Species: 68.21
UniProt: Q15813 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15813 NP_001072983.1 527 59346 S516 L K S L Q F Y S V E N G D C L
Chimpanzee Pan troglodytes XP_001154821 527 59309 S516 L K S L Q F Y S V E N G D C L
Rhesus Macaque Macaca mulatta XP_001100733 527 59584 S516 L Q S L R F Y S V E N E D C L
Dog Lupus familis XP_536339 528 59149 S517 Q Q S L Q F Y S V E S G D C L
Cat Felis silvestris
Mouse Mus musculus Q8CIV8 524 59067 S513 L Q P L Q F Y S V E N G D C L
Rat Rattus norvegicus Q5FVQ9 524 59024 S513 L Q P L Q F Y S V E N G D C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512384 490 54035 S482 L A G E G S G S T R H G H R V
Chicken Gallus gallus XP_423980 529 59195 S518 L K P L Q F Y S I E N G D S V
Frog Xenopus laevis Q5U508 522 58770 S511 L K P L Q F Y S V E N G D C L
Zebra Danio Brachydanio rerio Q5U378 521 59024 S509 L K P L Q F Y S V E D G D K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995747 523 59405 S513 A K T L D F Y S V Q E H D T V
Honey Bee Apis mellifera XP_001120710 465 53741 G458 S Y Y S I Q D G D Q V I V R W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782736 426 47879 S418 L G F F G I E S G N T I I I R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39937 518 59239 S510 S S P V N N K S I Q K V N S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 93.3 81.2 N.A. 74.5 75.3 N.A. 54.6 62.1 57.8 52.1 N.A. 31.8 34.5 N.A. 33
Protein Similarity: 100 99.6 96.3 89.9 N.A. 85.3 85.1 N.A. 65.8 74.4 72.3 68.6 N.A. 53.1 53.3 N.A. 49.1
P-Site Identity: 100 100 80 80 N.A. 86.6 86.6 N.A. 20 73.3 93.3 73.3 N.A. 46.6 0 N.A. 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 33.3 86.6 93.3 86.6 N.A. 66.6 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % C
% Asp: 0 0 0 0 8 0 8 0 8 0 8 0 72 0 0 % D
% Glu: 0 0 0 8 0 0 8 0 0 65 8 8 0 0 0 % E
% Phe: 0 0 8 8 0 72 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 15 0 8 8 8 0 0 65 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 8 8 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 15 0 0 15 8 8 8 % I
% Lys: 0 43 0 0 0 0 8 0 0 0 8 0 0 8 0 % K
% Leu: 72 0 0 72 0 0 0 0 0 0 0 0 0 0 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 8 50 0 8 0 0 % N
% Pro: 0 0 43 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 8 29 0 0 58 8 0 0 0 22 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 8 0 0 0 15 8 % R
% Ser: 15 8 29 8 0 8 0 93 0 0 8 0 0 15 0 % S
% Thr: 0 0 8 0 0 0 0 0 8 0 8 0 0 8 0 % T
% Val: 0 0 0 8 0 0 0 0 65 0 8 8 8 0 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 8 8 0 0 0 72 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _