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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCE
All Species:
20.61
Human Site:
T435
Identified Species:
34.87
UniProt:
Q15813
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15813
NP_001072983.1
527
59346
T435
P
E
D
W
E
L
K
T
Q
Q
P
L
M
L
K
Chimpanzee
Pan troglodytes
XP_001154821
527
59309
T435
P
E
D
W
E
L
K
T
Q
Q
P
L
M
L
K
Rhesus Macaque
Macaca mulatta
XP_001100733
527
59584
T435
P
E
D
W
E
L
K
T
Q
Q
P
F
M
L
K
Dog
Lupus familis
XP_536339
528
59149
T436
P
E
D
G
E
L
K
T
Q
Q
P
F
V
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIV8
524
59067
T432
P
E
D
E
E
L
K
T
Q
Q
P
F
M
L
K
Rat
Rattus norvegicus
Q5FVQ9
524
59024
T432
P
E
D
E
E
L
K
T
Q
Q
P
F
M
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512384
490
54035
A395
P
E
D
G
E
L
K
A
Q
Q
P
F
M
L
K
Chicken
Gallus gallus
XP_423980
529
59195
G437
P
E
E
G
E
L
K
G
Q
Q
P
L
T
L
R
Frog
Xenopus laevis
Q5U508
522
58770
Q430
P
D
E
G
E
L
K
Q
Q
Q
P
F
A
L
K
Zebra Danio
Brachydanio rerio
Q5U378
521
59024
E428
P
D
E
G
E
L
R
E
Q
K
P
F
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995747
523
59405
F433
K
Y
G
S
P
A
D
F
V
P
R
S
Q
A
K
Honey Bee
Apis mellifera
XP_001120710
465
53741
V379
S
K
T
K
V
E
M
V
S
N
V
I
T
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782736
426
47879
A339
D
S
Q
T
K
P
G
A
L
K
S
S
L
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39937
518
59239
Q422
N
N
E
R
E
T
R
Q
S
L
V
L
K
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.3
81.2
N.A.
74.5
75.3
N.A.
54.6
62.1
57.8
52.1
N.A.
31.8
34.5
N.A.
33
Protein Similarity:
100
99.6
96.3
89.9
N.A.
85.3
85.1
N.A.
65.8
74.4
72.3
68.6
N.A.
53.1
53.3
N.A.
49.1
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
80
66.6
60
46.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
80
80
73.3
73.3
N.A.
6.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
15
0
0
0
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
50
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
58
29
15
79
8
0
8
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
50
0
0
0
% F
% Gly:
0
0
8
36
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
8
8
0
8
8
0
65
0
0
15
0
0
8
0
79
% K
% Leu:
0
0
0
0
0
72
0
0
8
8
0
29
8
79
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
43
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
72
0
0
0
8
8
0
0
0
8
72
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
15
72
65
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
15
0
0
0
8
0
0
0
8
% R
% Ser:
8
8
0
8
0
0
0
0
15
0
8
15
0
0
0
% S
% Thr:
0
0
8
8
0
8
0
43
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
8
0
0
8
8
0
15
0
8
8
0
% V
% Trp:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _