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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCE
All Species:
32.42
Human Site:
Y425
Identified Species:
54.87
UniProt:
Q15813
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15813
NP_001072983.1
527
59346
Y425
Y
Q
F
L
C
L
K
Y
G
A
P
E
D
W
E
Chimpanzee
Pan troglodytes
XP_001154821
527
59309
Y425
Y
Q
F
L
C
L
K
Y
G
A
P
E
D
W
E
Rhesus Macaque
Macaca mulatta
XP_001100733
527
59584
Y425
Y
Q
F
L
C
L
K
Y
G
A
P
E
D
W
E
Dog
Lupus familis
XP_536339
528
59149
Y426
Y
Q
L
L
C
L
K
Y
G
A
P
E
D
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIV8
524
59067
Y422
Y
Q
L
L
C
C
K
Y
G
A
P
E
D
E
E
Rat
Rattus norvegicus
Q5FVQ9
524
59024
Y422
Y
Q
L
L
C
C
K
Y
G
A
P
E
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512384
490
54035
Y385
R
L
S
P
S
P
E
Y
G
A
P
E
D
G
E
Chicken
Gallus gallus
XP_423980
529
59195
Y427
Y
P
S
L
C
L
Q
Y
G
A
P
E
E
G
E
Frog
Xenopus laevis
Q5U508
522
58770
Y420
Y
S
A
L
I
K
K
Y
G
A
P
D
E
G
E
Zebra Danio
Brachydanio rerio
Q5U378
521
59024
Y418
Y
L
T
L
I
Q
K
Y
G
A
P
D
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995747
523
59405
L423
R
H
R
T
Y
P
L
L
V
K
K
Y
G
S
P
Honey Bee
Apis mellifera
XP_001120710
465
53741
I369
A
K
Y
G
I
S
D
I
P
S
S
K
T
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782736
426
47879
V329
K
K
Y
G
A
P
E
V
S
D
D
S
Q
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39937
518
59239
L412
Y
E
I
D
M
S
K
L
S
F
N
N
E
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.3
81.2
N.A.
74.5
75.3
N.A.
54.6
62.1
57.8
52.1
N.A.
31.8
34.5
N.A.
33
Protein Similarity:
100
99.6
96.3
89.9
N.A.
85.3
85.1
N.A.
65.8
74.4
72.3
68.6
N.A.
53.1
53.3
N.A.
49.1
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
46.6
66.6
53.3
53.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
53.3
80
66.6
66.6
N.A.
0
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
0
0
0
72
0
0
0
0
0
% A
% Cys:
0
0
0
0
50
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
8
8
15
50
0
0
% D
% Glu:
0
8
0
0
0
0
15
0
0
0
0
58
29
15
79
% E
% Phe:
0
0
22
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
0
0
72
0
0
0
8
36
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
22
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
15
0
0
0
8
65
0
0
8
8
8
0
8
8
% K
% Leu:
0
15
22
65
0
36
8
15
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
8
0
8
0
22
0
0
8
0
72
0
0
0
8
% P
% Gln:
0
43
0
0
0
8
8
0
0
0
0
0
8
0
0
% Q
% Arg:
15
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
15
0
8
15
0
0
15
8
8
8
0
8
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
22
0
% W
% Tyr:
72
0
15
0
8
0
0
72
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _