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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCE
All Species:
33.03
Human Site:
Y493
Identified Species:
55.9
UniProt:
Q15813
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15813
NP_001072983.1
527
59346
Y493
V
S
D
L
L
L
S
Y
E
S
P
K
K
P
G
Chimpanzee
Pan troglodytes
XP_001154821
527
59309
Y493
V
S
D
L
L
L
S
Y
E
S
P
K
K
P
G
Rhesus Macaque
Macaca mulatta
XP_001100733
527
59584
Y493
V
S
D
L
L
L
S
Y
E
S
P
K
E
P
G
Dog
Lupus familis
XP_536339
528
59149
Y494
V
S
E
L
L
L
S
Y
E
S
P
K
M
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIV8
524
59067
Y490
V
S
E
L
L
L
S
Y
E
S
S
K
M
P
G
Rat
Rattus norvegicus
Q5FVQ9
524
59024
Y490
V
S
E
L
L
L
S
Y
E
S
S
K
M
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512384
490
54035
Y453
G
S
E
L
R
L
S
Y
E
S
P
K
G
R
H
Chicken
Gallus gallus
XP_423980
529
59195
Y495
G
S
E
L
K
L
S
Y
E
S
S
K
L
K
G
Frog
Xenopus laevis
Q5U508
522
58770
Y488
G
S
D
L
K
L
S
Y
Q
S
S
K
M
E
G
Zebra Danio
Brachydanio rerio
Q5U378
521
59024
Y486
G
V
E
L
K
L
T
Y
T
C
A
K
M
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995747
523
59405
Y490
G
D
V
P
Q
L
C
Y
V
D
A
L
H
P
D
Honey Bee
Apis mellifera
XP_001120710
465
53741
L436
L
S
F
I
Q
Q
N
L
S
K
D
E
I
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782736
426
47879
K396
K
L
F
Y
L
S
P
K
L
P
D
Q
E
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39937
518
59239
E481
N
S
E
G
M
I
N
E
I
K
Y
N
F
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.3
81.2
N.A.
74.5
75.3
N.A.
54.6
62.1
57.8
52.1
N.A.
31.8
34.5
N.A.
33
Protein Similarity:
100
99.6
96.3
89.9
N.A.
85.3
85.1
N.A.
65.8
74.4
72.3
68.6
N.A.
53.1
53.3
N.A.
49.1
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
60
60
60
26.6
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
66.6
66.6
66.6
40
N.A.
20
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
15
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
29
0
0
0
0
0
0
8
15
0
0
0
15
% D
% Glu:
0
0
50
0
0
0
0
8
58
0
0
8
15
8
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
36
0
0
8
0
0
0
0
0
0
0
0
8
0
58
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
8
0
8
0
0
8
0
0
0
8
8
0
% I
% Lys:
8
0
0
0
22
0
0
8
0
15
0
72
15
8
0
% K
% Leu:
8
8
0
72
50
79
0
8
8
0
0
8
8
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
36
0
0
% M
% Asn:
8
0
0
0
0
0
15
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
8
36
0
0
58
15
% P
% Gln:
0
0
0
0
15
8
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
15
0
% R
% Ser:
0
79
0
0
0
8
65
0
8
65
29
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% T
% Val:
43
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
79
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _