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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCC All Species: 43.94
Human Site: S334 Identified Species: 74.36
UniProt: Q15814 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15814 NP_003183.1 346 39220 S334 D M A S P N W S I L P E E E R
Chimpanzee Pan troglodytes XP_518477 346 39236 S334 D M A S P N W S I L P E E E R
Rhesus Macaque Macaca mulatta XP_001088723 346 39322 S334 D M A S P N W S I L P E E E R
Dog Lupus familis XP_538923 388 42549 S376 D T A S P N W S I L P E E E R
Cat Felis silvestris
Mouse Mus musculus Q8VCN9 341 38106 S329 N V A S P N W S I L P E E E R
Rat Rattus norvegicus NP_001101670 340 38058 S328 N V P S P N W S I L P E E D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508991 335 37102 S323 G V A S P N W S V L P E E E R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922489 350 39443 T329 G T P S P N W T V I P E S E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722959 355 40503 S319 D V P S P N W S L L K D Y P D
Honey Bee Apis mellifera XP_001120828 342 39209 S330 E K H S P N W S I L D P E L R
Nematode Worm Caenorhab. elegans Q27249 256 29613 T249 L T E E I E Q T V Q E I Q G S
Sea Urchin Strong. purpuratus XP_783718 353 39965 G341 D K H S P N W G L L P E D E R
Poplar Tree Populus trichocarpa XP_002307082 324 36492 S311 A V K S P N W S V L E E S E R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195702 345 38291 S328 A V Q S P N W S L L P E E E R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.3 72.9 N.A. 76 74.5 N.A. 61.5 N.A. N.A. 43.7 N.A. 33.5 38.7 21.1 39.6
Protein Similarity: 100 99.1 97.6 78.3 N.A. 84.3 83.5 N.A. 74.5 N.A. N.A. 64 N.A. 57.7 58 40.1 62.6
P-Site Identity: 100 100 100 93.3 N.A. 86.6 73.3 N.A. 80 N.A. N.A. 53.3 N.A. 46.6 60 0 66.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 73.3 N.A. 66.6 66.6 20 80
Percent
Protein Identity: 29.7 N.A. N.A. 32.3 N.A. N.A.
Protein Similarity: 48.2 N.A. N.A. 51.7 N.A. N.A.
P-Site Identity: 60 N.A. N.A. 73.3 N.A. N.A.
P-Site Similarity: 73.3 N.A. N.A. 86.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 43 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 43 0 0 0 0 0 0 0 0 0 8 8 8 8 8 % D
% Glu: 8 0 8 8 0 8 0 0 0 0 15 79 65 72 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % G
% His: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 50 8 0 8 0 0 0 % I
% Lys: 0 15 8 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 22 86 0 0 0 8 0 % L
% Met: 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 22 0 93 0 0 0 0 0 72 8 0 8 0 % P
% Gln: 0 0 8 0 0 0 8 0 0 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 % R
% Ser: 0 0 0 93 0 0 0 79 0 0 0 0 15 0 8 % S
% Thr: 0 22 0 0 0 0 0 15 0 0 0 0 0 0 0 % T
% Val: 0 43 0 0 0 0 0 0 29 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _