KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
10.91
Human Site:
S89
Identified Species:
18.46
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S89
E
R
L
E
E
A
A
S
R
L
Q
G
L
Q
K
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S89
E
R
L
E
E
A
A
S
R
L
Q
G
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S89
E
G
L
E
E
A
A
S
R
L
Q
G
L
Q
K
Dog
Lupus familis
XP_538923
388
42549
A131
E
Q
L
D
E
A
A
A
R
L
Q
G
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
N88
E
R
L
E
E
A
A
N
R
L
Q
G
L
R
K
Rat
Rattus norvegicus
NP_001101670
340
38058
N88
E
R
L
E
E
A
A
N
R
L
Q
A
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
A89
R
D
L
D
E
A
A
A
R
L
R
G
L
Q
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
V91
K
T
L
E
E
A
T
V
K
F
Q
Q
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
V84
R
N
F
A
D
I
T
V
E
I
Q
D
L
Q
R
Honey Bee
Apis mellifera
XP_001120828
342
39209
K81
G
I
F
D
K
I
N
K
E
I
Q
M
L
K
N
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
R26
K
K
K
M
R
Q
A
R
E
E
A
E
A
A
K
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
E103
D
F
F
D
D
I
T
E
V
A
Q
K
L
Q
K
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
S78
S
H
L
A
N
I
S
S
S
I
S
S
L
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
V95
S
D
L
A
E
I
S
V
A
I
D
N
L
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
93.3
80
N.A.
86.6
80
N.A.
66.6
N.A.
N.A.
53.3
N.A.
20
13.3
13.3
26.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
66.6
N.A.
40
40
26.6
46.6
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
0
58
58
15
8
8
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
29
15
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
43
0
0
43
65
0
0
8
22
8
0
8
0
15
0
% E
% Phe:
0
8
22
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
43
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
36
0
0
0
29
0
0
0
0
0
% I
% Lys:
15
8
8
0
8
0
0
8
8
0
0
8
0
8
86
% K
% Leu:
0
0
72
0
0
0
0
0
0
50
0
0
93
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
8
0
8
15
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
72
8
0
58
0
% Q
% Arg:
15
29
0
0
8
0
0
8
50
0
8
0
0
15
8
% R
% Ser:
15
0
0
0
0
0
15
29
8
0
8
8
0
0
0
% S
% Thr:
0
8
0
0
0
0
22
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
22
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _