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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPTX1
All Species:
27.27
Human Site:
S168
Identified Species:
66.67
UniProt:
Q15818
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15818
NP_002513.2
432
47122
S168
S
L
K
D
L
L
Q
S
K
I
D
E
L
E
R
Chimpanzee
Pan troglodytes
XP_523739
432
47074
S168
S
L
K
D
L
L
Q
S
K
I
D
E
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001110666
976
104392
S712
S
L
K
D
L
L
Q
S
K
I
D
E
L
E
R
Dog
Lupus familis
XP_540475
432
47159
S168
T
L
K
D
L
L
Q
S
K
I
D
D
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62443
432
47099
S168
S
L
K
D
L
L
Q
S
K
I
D
D
L
E
R
Rat
Rattus norvegicus
P47971
432
47198
S168
S
L
K
D
L
L
Q
S
K
I
D
D
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512220
445
48650
R179
F
R
E
M
L
Q
R
R
L
G
E
L
E
R
Q
Chicken
Gallus gallus
XP_414750
489
53230
R223
L
R
E
M
L
Q
R
R
L
G
D
L
E
R
Q
Frog
Xenopus laevis
NP_001091445
435
48766
N171
S
L
K
D
L
L
Q
N
K
I
D
D
L
E
K
Zebra Danio
Brachydanio rerio
NP_998101
432
48122
S168
S
L
K
D
L
L
Q
S
K
I
D
D
L
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
44.1
95.8
N.A.
96.3
95.8
N.A.
56.1
53.3
77
76.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
44.1
98.3
N.A.
98.3
98.1
N.A.
72.8
69.7
87.3
87.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
6.6
13.3
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
33.3
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
80
0
0
0
0
0
0
90
50
0
0
0
% D
% Glu:
0
0
20
0
0
0
0
0
0
0
10
30
20
80
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% I
% Lys:
0
0
80
0
0
0
0
0
80
0
0
0
0
0
20
% K
% Leu:
10
80
0
0
100
80
0
0
20
0
0
20
80
0
0
% L
% Met:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
20
80
0
0
0
0
0
0
0
20
% Q
% Arg:
0
20
0
0
0
0
20
20
0
0
0
0
0
20
60
% R
% Ser:
70
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _