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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA2
All Species:
17.27
Human Site:
S398
Identified Species:
38
UniProt:
Q15822
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15822
NP_000733.2
529
59735
S398
H
P
L
R
L
K
L
S
P
S
Y
H
W
L
E
Chimpanzee
Pan troglodytes
Q5IS52
529
59755
S398
H
P
L
H
L
K
L
S
P
S
Y
H
W
L
E
Rhesus Macaque
Macaca mulatta
XP_001109335
529
59676
S398
H
P
P
G
L
K
L
S
P
S
Y
H
W
L
E
Dog
Lupus familis
XP_543227
490
55911
E371
E
T
N
V
D
A
E
E
R
E
E
E
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91X60
512
58717
S375
G
S
P
G
L
K
L
S
P
T
Y
H
W
L
E
Rat
Rattus norvegicus
P12389
511
58593
S375
G
S
P
D
L
K
L
S
P
S
Y
H
W
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
M828
L
N
L
L
P
K
I
M
F
M
T
R
P
G
S
Chicken
Gallus gallus
P09480
528
60656
S379
D
P
P
G
T
R
L
S
T
S
R
C
W
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035417
520
59749
M394
D
G
L
V
C
Q
D
M
E
F
G
I
G
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
I416
D
L
A
A
A
G
G
I
S
A
H
C
F
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
Q378
Y
L
L
M
T
R
P
Q
P
P
G
H
H
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
83.7
N.A.
82.4
82
N.A.
32.1
74.6
N.A.
70.3
N.A.
46.2
N.A.
47.4
N.A.
Protein Similarity:
100
99.6
98.1
86
N.A.
86.1
85.4
N.A.
40.5
80.3
N.A.
77.8
N.A.
60.3
N.A.
63.1
N.A.
P-Site Identity:
100
93.3
86.6
6.6
N.A.
66.6
73.3
N.A.
13.3
46.6
N.A.
13.3
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
93.3
86.6
6.6
N.A.
73.3
73.3
N.A.
20
53.3
N.A.
20
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
10
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
19
0
0
0
% C
% Asp:
28
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
10
10
10
10
10
0
10
73
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% F
% Gly:
19
10
0
28
0
10
10
0
0
0
19
0
19
10
0
% G
% His:
28
0
0
10
0
0
0
0
0
0
10
55
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
19
46
10
46
0
55
0
0
0
0
0
0
64
0
% L
% Met:
0
0
0
10
0
0
0
19
0
10
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
37
37
0
10
0
10
0
55
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
19
0
0
10
0
10
10
0
0
0
% R
% Ser:
0
19
0
0
0
0
0
55
10
46
0
0
0
10
19
% S
% Thr:
0
10
0
0
19
0
0
0
10
10
10
0
0
0
0
% T
% Val:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _