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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA6
All Species:
12.12
Human Site:
S367
Identified Species:
24.24
UniProt:
Q15825
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15825
NP_004189.1
494
56898
S367
D
K
T
R
G
T
G
S
D
A
V
P
R
G
L
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
S367
D
K
T
R
G
T
G
S
D
A
V
P
R
G
L
Rhesus Macaque
Macaca mulatta
XP_001099152
494
57084
S367
D
K
T
G
G
T
G
S
D
T
V
P
R
G
L
Dog
Lupus familis
XP_539951
483
56068
N359
R
K
T
S
S
D
K
N
S
K
G
I
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0W9
494
56789
G367
D
K
T
K
E
A
G
G
V
K
D
P
K
S
H
Rat
Rattus norvegicus
P43143
493
56929
G367
D
K
T
K
E
M
D
G
V
K
D
P
K
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509745
552
63776
S384
E
K
K
V
E
K
F
S
D
K
D
S
K
G
F
Chicken
Gallus gallus
P49581
494
57476
S367
E
Q
E
K
K
N
I
S
K
K
T
K
K
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036149
512
57984
N384
G
E
G
K
K
R
K
N
S
G
S
Q
Q
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17644
576
65488
A388
D
L
L
R
D
L
A
A
N
K
I
N
Y
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
H382
T
R
P
Q
P
P
G
H
H
S
K
P
N
R
K
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
P412
R
Y
N
H
G
E
N
P
N
K
E
K
D
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
85.8
N.A.
84.6
84.6
N.A.
73.9
79.1
N.A.
69.1
N.A.
40.6
N.A.
46
44.7
Protein Similarity:
100
99.8
97.3
90.2
N.A.
90
90.2
N.A.
79.5
88
N.A.
79.6
N.A.
58.3
N.A.
64.3
61.2
P-Site Identity:
100
100
86.6
13.3
N.A.
33.3
26.6
N.A.
26.6
13.3
N.A.
6.6
N.A.
26.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
86.6
20
N.A.
46.6
40
N.A.
40
40
N.A.
33.3
N.A.
46.6
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
9
0
17
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
9
9
9
0
34
0
25
0
9
0
0
% D
% Glu:
17
9
9
0
25
9
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% F
% Gly:
9
0
9
9
34
0
42
17
0
9
9
0
0
59
0
% G
% His:
0
0
0
9
0
0
0
9
9
0
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% I
% Lys:
0
59
9
34
17
9
17
0
9
59
9
17
34
0
9
% K
% Leu:
0
9
9
0
0
9
0
0
0
0
0
0
0
9
34
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
9
17
17
0
0
9
9
0
9
% N
% Pro:
0
0
9
0
9
9
0
9
0
0
0
50
0
0
0
% P
% Gln:
0
9
0
9
0
0
0
0
0
0
0
9
9
0
0
% Q
% Arg:
17
9
0
25
0
9
0
0
0
0
0
0
25
9
9
% R
% Ser:
0
0
0
9
9
0
0
42
17
9
9
9
9
17
9
% S
% Thr:
9
0
50
0
0
25
0
0
0
9
9
0
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
17
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _