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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA6
All Species:
13.64
Human Site:
S407
Identified Species:
27.27
UniProt:
Q15825
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15825
NP_004189.1
494
56898
S407
K
S
N
E
L
A
T
S
K
R
R
L
S
H
Q
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
S407
K
S
N
E
L
A
T
S
K
R
R
L
S
H
H
Rhesus Macaque
Macaca mulatta
XP_001099152
494
57084
S407
K
S
N
E
L
A
T
S
K
R
R
L
N
H
Q
Dog
Lupus familis
XP_539951
483
56068
S396
K
S
S
K
L
A
T
S
K
R
R
L
S
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0W9
494
56789
G407
K
S
S
D
I
A
P
G
K
R
R
S
S
Q
Q
Rat
Rattus norvegicus
P43143
493
56929
P406
H
K
S
S
E
I
A
P
G
K
R
L
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509745
552
63776
N424
P
S
N
E
L
S
S
N
K
R
R
L
S
Y
H
Chicken
Gallus gallus
P49581
494
57476
R410
A
D
D
L
T
S
T
R
R
S
R
L
S
H
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036149
512
57984
V427
T
E
G
D
C
G
K
V
S
R
Q
L
S
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17644
576
65488
S468
S
G
Y
N
G
L
P
S
V
L
S
G
L
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
N419
L
S
P
G
L
N
S
N
R
E
E
S
S
F
T
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
D457
K
L
R
T
L
S
D
D
V
G
N
P
N
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
85.8
N.A.
84.6
84.6
N.A.
73.9
79.1
N.A.
69.1
N.A.
40.6
N.A.
46
44.7
Protein Similarity:
100
99.8
97.3
90.2
N.A.
90
90.2
N.A.
79.5
88
N.A.
79.6
N.A.
58.3
N.A.
64.3
61.2
P-Site Identity:
100
93.3
93.3
86.6
N.A.
53.3
26.6
N.A.
60
40
N.A.
26.6
N.A.
6.6
N.A.
20
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
73.3
40
N.A.
86.6
60
N.A.
40
N.A.
6.6
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
42
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
17
0
0
9
9
0
0
0
0
0
9
17
% D
% Glu:
0
9
0
34
9
0
0
0
0
9
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
9
9
9
9
9
0
9
9
9
0
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
42
17
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
9
0
% I
% Lys:
50
9
0
9
0
0
9
0
50
9
0
0
0
0
0
% K
% Leu:
9
9
0
9
59
9
0
0
0
9
0
67
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
34
9
0
9
0
17
0
0
9
0
17
0
0
% N
% Pro:
9
0
9
0
0
0
17
9
0
0
0
9
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
17
59
% Q
% Arg:
0
0
9
0
0
0
0
9
17
59
67
0
0
0
0
% R
% Ser:
9
59
25
9
0
25
17
42
9
9
9
17
75
0
0
% S
% Thr:
9
0
0
9
9
0
42
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
9
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _