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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STK11 All Species: 43.64
Human Site: S169 Identified Species: 68.57
UniProt: Q15831 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15831 NP_000446.1 433 48636 S169 D G L E Y L H S Q G I V H K D
Chimpanzee Pan troglodytes XP_524028 433 48572 S169 D G L E Y L H S Q G I V H K D
Rhesus Macaque Macaca mulatta XP_001093806 433 48511 S169 D G L E Y L H S Q G I V H K D
Dog Lupus familis XP_542206 439 49298 S169 D G L E Y L H S Q G I V H K D
Cat Felis silvestris
Mouse Mus musculus Q9WTK7 436 49248 S169 D G L E Y L H S Q G I V H K D
Rat Rattus norvegicus NP_001101539 436 49227 S169 D G L E Y L H S Q G I V H K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519859 324 36639 R75 I E L L R R L R H K N V I Q L
Chicken Gallus gallus Q0GGW5 440 49774 S169 D G L E Y L H S Q G I V H K D
Frog Xenopus laevis Q91604 432 49054 S172 D G L E Y L H S Q G I V H K D
Zebra Danio Brachydanio rerio NP_001017839 440 49807 S168 D G L E Y L H S Q G I V H K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650302 567 62874 S292 D G L E Y L H S C R V I H K D
Honey Bee Apis mellifera XP_623596 434 50409 K172 M L G S T P L K K L P I W Q A
Nematode Worm Caenorhab. elegans Q9GN62 617 69630 S303 Q G L N Y L H S K R V S H K D
Sea Urchin Strong. purpuratus XP_780778 429 48923 K162 M L D A A E C K K F P I W Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 E133 E L F D Y I V E K G R L Q E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.3 92.4 N.A. 90.1 90.5 N.A. 57.7 89.3 81.2 82.2 N.A. 41.4 54.6 29.8 57.7
Protein Similarity: 100 99.3 99.5 94.5 N.A. 93.3 93.1 N.A. 63.2 93.1 87.5 87.2 N.A. 54.8 71.8 43.7 72.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 100 100 N.A. 73.3 0 60 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 100 100 100 N.A. 86.6 20 73.3 20
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % C
% Asp: 67 0 7 7 0 0 0 0 0 0 0 0 0 0 80 % D
% Glu: 7 7 0 67 0 7 0 7 0 0 0 0 0 7 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 74 7 0 0 0 0 0 0 67 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 74 0 7 0 0 0 74 0 0 % H
% Ile: 7 0 0 0 0 7 0 0 0 0 60 20 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 14 27 7 0 0 0 74 0 % K
% Leu: 0 20 80 7 0 74 14 0 0 7 0 7 0 0 7 % L
% Met: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 14 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 60 0 0 0 7 20 0 % Q
% Arg: 0 0 0 0 7 7 0 7 0 14 7 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 0 74 0 0 0 7 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 7 0 0 0 14 67 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % W
% Tyr: 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _