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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK11
All Species:
41.52
Human Site:
T185
Identified Species:
65.24
UniProt:
Q15831
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15831
NP_000446.1
433
48636
T185
K
P
G
N
L
L
L
T
T
G
G
T
L
K
I
Chimpanzee
Pan troglodytes
XP_524028
433
48572
T185
K
P
G
N
L
L
L
T
T
G
G
T
L
K
I
Rhesus Macaque
Macaca mulatta
XP_001093806
433
48511
T185
K
P
G
N
L
L
L
T
T
G
G
T
L
K
I
Dog
Lupus familis
XP_542206
439
49298
T185
K
P
G
N
L
L
L
T
T
S
G
T
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK7
436
49248
T185
K
P
G
N
L
L
L
T
T
N
G
T
L
K
I
Rat
Rattus norvegicus
NP_001101539
436
49227
T185
K
P
G
N
L
L
L
T
T
N
G
T
L
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519859
324
36639
E90
V
D
V
L
Y
N
E
E
K
Q
K
M
Y
M
V
Chicken
Gallus gallus
Q0GGW5
440
49774
T185
K
P
G
N
L
L
L
T
T
N
G
T
L
K
I
Frog
Xenopus laevis
Q91604
432
49054
T188
K
P
G
N
L
L
L
T
T
D
G
T
L
K
I
Zebra Danio
Brachydanio rerio
NP_001017839
440
49807
T184
K
P
G
N
L
L
L
T
T
D
G
A
L
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650302
567
62874
S308
K
P
G
N
L
L
L
S
L
D
Q
T
L
K
I
Honey Bee
Apis mellifera
XP_623596
434
50409
D188
D
Y
F
C
Q
L
L
D
G
L
E
Y
L
Y
S
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
S319
K
P
G
N
L
L
V
S
I
D
F
T
V
K
I
Sea Urchin
Strong. purpuratus
XP_780778
429
48923
L183
L
V
D
G
L
E
Y
L
H
S
Q
H
V
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
V161
E
Y
C
H
R
N
M
V
V
H
R
D
L
K
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
92.4
N.A.
90.1
90.5
N.A.
57.7
89.3
81.2
82.2
N.A.
41.4
54.6
29.8
57.7
Protein Similarity:
100
99.3
99.5
94.5
N.A.
93.3
93.1
N.A.
63.2
93.1
87.5
87.2
N.A.
54.8
71.8
43.7
72.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
93.3
93.3
86.6
N.A.
73.3
20
60
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
93.3
93.3
86.6
N.A.
80
20
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
0
0
0
7
0
27
0
7
0
0
0
% D
% Glu:
7
0
0
0
0
7
7
7
0
0
7
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
74
7
0
0
0
0
7
20
60
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
7
7
0
7
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
74
% I
% Lys:
74
0
0
0
0
0
0
0
7
0
7
0
0
80
0
% K
% Leu:
7
0
0
7
80
80
74
7
7
7
0
0
80
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
7
0
7
0
% M
% Asn:
0
0
0
74
0
14
0
0
0
20
0
0
0
0
0
% N
% Pro:
0
74
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
7
14
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
14
0
14
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
60
60
0
0
67
0
0
0
% T
% Val:
7
7
7
0
0
0
7
7
7
0
0
0
14
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
7
0
7
0
0
0
0
7
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _