Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STK11 All Species: 31.52
Human Site: T328 Identified Species: 49.52
UniProt: Q15831 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15831 NP_000446.1 433 48636 T328 P I P P S P D T K D R W R S M
Chimpanzee Pan troglodytes XP_524028 433 48572 T328 P I P P S P D T K D R W R S M
Rhesus Macaque Macaca mulatta XP_001093806 433 48511 T328 P I P P S P D T K D R W R S M
Dog Lupus familis XP_542206 439 49298 C328 P I P P S T D C K D R W R G M
Cat Felis silvestris
Mouse Mus musculus Q9WTK7 436 49248 T328 P I P P S P D T K D R W R S M
Rat Rattus norvegicus NP_001101539 436 49227 T328 P I P P S P D T K D R W R S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519859 324 36639 I229 Y P F E G D N I Y K L F E N I
Chicken Gallus gallus Q0GGW5 440 49774 T328 P I P P S P E T K D K W R S M
Frog Xenopus laevis Q91604 432 49054 T331 P I P P S P E T K D R W R S L
Zebra Danio Brachydanio rerio NP_001017839 440 49807 T327 P I P P S A E T R D R W R S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650302 567 62874 K452 P I P I P P L K G D K Y R N S
Honey Bee Apis mellifera XP_623596 434 50409 K330 R F T L Q Q V K K H P W T I C
Nematode Worm Caenorhab. elegans Q9GN62 617 69630 M463 L G R I M E R M R T G D R P L
Sea Urchin Strong. purpuratus XP_780778 429 48923 V325 Q I K E H V W V R K K H D L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 R341 L I E S L R N R T Q N D G T V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.3 92.4 N.A. 90.1 90.5 N.A. 57.7 89.3 81.2 82.2 N.A. 41.4 54.6 29.8 57.7
Protein Similarity: 100 99.3 99.5 94.5 N.A. 93.3 93.1 N.A. 63.2 93.1 87.5 87.2 N.A. 54.8 71.8 43.7 72.2
P-Site Identity: 100 100 100 80 N.A. 100 100 N.A. 0 86.6 86.6 80 N.A. 40 13.3 6.6 6.6
P-Site Similarity: 100 100 100 80 N.A. 100 100 N.A. 26.6 100 100 93.3 N.A. 60 13.3 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 0 0 7 40 0 0 67 0 14 7 0 0 % D
% Glu: 0 0 7 14 0 7 20 0 0 0 0 0 7 0 0 % E
% Phe: 0 7 7 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 7 0 0 7 0 0 0 7 0 7 0 7 7 0 % G
% His: 0 0 0 0 7 0 0 0 0 7 0 7 0 0 0 % H
% Ile: 0 80 0 14 0 0 0 7 0 0 0 0 0 7 7 % I
% Lys: 0 0 7 0 0 0 0 14 60 14 20 0 0 0 0 % K
% Leu: 14 0 0 7 7 0 7 0 0 0 7 0 0 7 14 % L
% Met: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 54 % M
% Asn: 0 0 0 0 0 0 14 0 0 0 7 0 0 14 0 % N
% Pro: 67 7 67 60 7 54 0 0 0 0 7 0 0 7 0 % P
% Gln: 7 0 0 0 7 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 7 0 0 7 7 7 20 0 54 0 74 0 0 % R
% Ser: 0 0 0 7 60 0 0 0 0 0 0 0 0 54 7 % S
% Thr: 0 0 7 0 0 7 0 54 7 7 0 0 7 7 0 % T
% Val: 0 0 0 0 0 7 7 7 0 0 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 67 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _