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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK11
All Species:
41.52
Human Site:
Y261
Identified Species:
65.24
UniProt:
Q15831
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15831
NP_000446.1
433
48636
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Chimpanzee
Pan troglodytes
XP_524028
433
48572
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Rhesus Macaque
Macaca mulatta
XP_001093806
433
48511
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Dog
Lupus familis
XP_542206
439
49298
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK7
436
49248
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Rat
Rattus norvegicus
NP_001101539
436
49227
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519859
324
36639
G165
T
L
K
I
S
D
L
G
V
A
E
A
L
H
P
Chicken
Gallus gallus
Q0GGW5
440
49774
Y261
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Frog
Xenopus laevis
Q91604
432
49054
Y264
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Zebra Danio
Brachydanio rerio
NP_001017839
440
49807
Y260
P
F
E
G
D
N
I
Y
K
L
F
E
N
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650302
567
62874
Y384
P
F
E
G
D
N
I
Y
R
L
L
E
N
I
G
Honey Bee
Apis mellifera
XP_623596
434
50409
S266
G
F
K
V
D
I
W
S
S
G
V
T
L
Y
N
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
L396
P
F
E
K
P
V
L
L
K
L
Y
E
C
I
G
Sea Urchin
Strong. purpuratus
XP_780778
429
48923
I259
V
D
I
W
S
S
G
I
T
L
Y
N
I
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
P246
P
F
D
D
E
N
I
P
N
L
F
K
K
I
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
92.4
N.A.
90.1
90.5
N.A.
57.7
89.3
81.2
82.2
N.A.
41.4
54.6
29.8
57.7
Protein Similarity:
100
99.3
99.5
94.5
N.A.
93.3
93.1
N.A.
63.2
93.1
87.5
87.2
N.A.
54.8
71.8
43.7
72.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
86.6
13.3
53.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
93.3
20
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
7
7
7
74
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
74
0
7
0
0
0
0
0
7
74
0
0
0
% E
% Phe:
0
87
0
0
0
0
0
0
0
0
67
0
0
0
0
% F
% Gly:
7
0
0
67
0
0
7
7
0
7
0
0
0
0
74
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
7
7
0
7
74
7
0
0
0
0
7
80
0
% I
% Lys:
0
0
14
7
0
0
0
0
67
0
0
7
7
0
7
% K
% Leu:
0
7
0
0
0
0
14
7
0
87
7
0
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
74
0
0
7
0
0
7
67
0
7
% N
% Pro:
80
0
0
0
7
0
0
7
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
14
7
0
7
7
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% T
% Val:
7
0
0
7
0
7
0
0
7
0
7
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
14
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _