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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
4.24
Human Site:
S347
Identified Species:
7.78
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S347
V
E
L
L
D
G
Q
S
K
T
K
G
Y
A
G
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
Q340
A
T
E
I
P
E
G
Q
R
V
R
G
R
V
G
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
P148
S
Q
D
G
L
F
Q
P
L
L
Q
A
T
L
A
Dog
Lupus familis
XP_542675
460
51324
E280
A
L
G
V
T
L
Y
E
M
I
A
A
R
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
N347
V
E
L
K
E
G
Q
N
K
T
K
G
Y
A
G
Rat
Rattus norvegicus
Q63651
564
63750
N347
V
E
L
K
E
G
Q
N
K
T
K
G
Y
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
T347
V
E
L
K
D
G
Q
T
K
T
K
G
Y
A
G
Chicken
Gallus gallus
NP_990026
593
64642
N377
V
E
L
K
D
G
Q
N
K
T
R
G
Y
A
G
Frog
Xenopus laevis
NP_001087513
575
66421
Q340
A
V
H
I
P
E
D
Q
T
I
K
G
R
V
G
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
N253
C
K
E
N
I
E
P
N
G
T
T
S
T
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
E464
A
V
E
I
P
E
G
E
M
V
R
G
R
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
E357
A
V
E
I
K
D
N
E
P
I
K
G
R
V
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
D566
L
S
K
A
D
L
K
D
R
T
N
T
F
C
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
13.3
6.6
0
N.A.
80
80
N.A.
86.6
80
20
6.6
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
33.3
20
6.6
N.A.
93.3
93.3
N.A.
93.3
93.3
26.6
20
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
8
0
0
0
0
0
0
8
16
0
39
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
8
0
31
8
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
39
31
0
16
31
0
24
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
8
8
0
39
16
0
8
0
0
70
0
8
77
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
31
8
0
0
0
0
24
0
0
0
0
0
% I
% Lys:
0
8
8
31
8
0
8
0
39
0
47
0
0
0
0
% K
% Leu:
8
8
39
8
8
16
0
0
8
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
31
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
24
0
8
8
8
0
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
47
16
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
16
0
24
0
39
0
0
% R
% Ser:
8
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% S
% Thr:
0
8
0
0
8
0
0
8
8
54
8
8
16
0
0
% T
% Val:
39
24
0
8
0
0
0
0
0
16
0
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
39
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _