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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
14.24
Human Site:
S45
Identified Species:
26.11
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S45
K
L
K
L
P
P
L
S
K
C
E
S
L
R
D
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
L45
P
V
S
Q
C
S
E
L
R
H
S
I
E
K
D
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
Dog
Lupus familis
XP_542675
460
51324
S25
A
R
G
S
F
D
G
S
S
G
P
S
S
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
S45
K
L
R
L
P
P
L
S
K
C
E
G
L
R
D
Rat
Rattus norvegicus
Q63651
564
63750
S45
K
L
R
L
P
P
L
S
K
C
E
G
L
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
S45
R
L
R
L
P
P
L
S
K
C
E
A
L
R
D
Chicken
Gallus gallus
NP_990026
593
64642
E45
L
P
H
I
S
Q
C
E
A
L
R
A
R
L
A
Frog
Xenopus laevis
NP_001087513
575
66421
L45
H
I
S
E
C
E
E
L
R
R
S
L
D
R
D
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
K46
I
S
Q
C
I
N
L
K
D
K
L
D
I
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
K45
Y
T
E
C
L
P
L
K
T
E
I
E
V
T
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
N165
S
T
S
S
L
S
I
N
Q
R
E
A
A
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
6.6
0
26.6
N.A.
86.6
86.6
N.A.
80
0
13.3
0
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
0
26.6
N.A.
93.3
93.3
N.A.
100
13.3
26.6
0
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
8
0
0
24
8
8
16
% A
% Cys:
0
0
0
16
16
0
8
0
0
31
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
0
8
8
0
54
% D
% Glu:
0
0
8
8
0
8
16
8
0
8
39
8
8
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
0
0
8
0
16
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
0
8
8
0
8
0
0
0
8
8
8
0
0
% I
% Lys:
24
0
8
0
0
0
0
16
31
8
0
0
0
8
0
% K
% Leu:
8
31
0
31
16
0
47
16
0
8
8
8
31
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
31
39
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
8
8
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
24
0
0
0
0
0
16
16
8
0
8
47
0
% R
% Ser:
8
8
24
16
8
16
0
39
8
0
16
16
8
8
0
% S
% Thr:
0
16
0
0
0
0
0
0
8
0
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _