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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
2.73
Human Site:
S553
Identified Species:
5
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S553
G
I
S
G
G
S
S
S
S
S
K
S
G
M
C
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
V520
N
E
G
C
L
T
M
V
P
S
E
K
E
V
E
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
K319
R
I
V
Y
R
D
L
K
P
E
N
V
L
L
D
Dog
Lupus familis
XP_542675
460
51324
A451
A
V
E
E
A
A
P
A
S
K
S
G
M
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
A553
G
I
T
T
E
E
A
A
P
T
A
K
S
G
M
Rat
Rattus norvegicus
Q63651
564
63750
A553
G
I
T
V
E
E
A
A
P
T
A
K
S
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
T553
D
G
P
G
E
D
E
T
A
S
S
S
K
S
G
Chicken
Gallus gallus
NP_990026
593
64642
G582
P
N
A
E
P
G
S
G
G
G
T
R
S
A
T
Frog
Xenopus laevis
NP_001087513
575
66421
Q546
W
R
G
L
P
S
P
Q
P
K
K
G
L
L
Q
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
S424
T
E
A
F
L
G
F
S
Y
A
P
A
M
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
D674
I
N
A
A
P
E
P
D
K
A
G
C
F
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
D577
R
P
D
G
I
N
M
D
E
R
R
N
G
T
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
N799
F
N
Q
E
K
N
M
N
N
S
H
S
Q
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
13.3
13.3
N.A.
20
6.6
13.3
6.6
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
13.3
26.6
N.A.
40
40
N.A.
33.3
13.3
20
26.6
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
8
8
8
16
24
8
16
16
8
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
8
% C
% Asp:
8
0
8
0
0
16
0
16
0
0
0
0
0
8
16
% D
% Glu:
0
16
8
24
24
24
8
0
8
8
8
0
8
0
8
% E
% Phe:
8
0
0
8
0
0
8
0
0
0
0
0
8
0
8
% F
% Gly:
24
8
16
24
8
16
0
8
8
8
8
16
16
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
31
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
8
16
16
24
8
0
0
% K
% Leu:
0
0
0
8
16
0
8
0
0
0
0
0
16
16
8
% L
% Met:
0
0
0
0
0
0
24
0
0
0
0
0
16
16
16
% M
% Asn:
8
24
0
0
0
16
0
8
8
0
8
8
0
0
0
% N
% Pro:
8
8
8
0
24
0
24
0
39
0
8
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% Q
% Arg:
16
8
0
0
8
0
0
0
0
8
8
8
0
0
0
% R
% Ser:
0
0
8
0
0
16
16
16
16
31
16
24
24
8
16
% S
% Thr:
8
0
16
8
0
8
0
8
0
16
8
0
0
8
8
% T
% Val:
0
8
8
8
0
0
0
8
0
0
0
8
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _