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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
3.33
Human Site:
S557
Identified Species:
6.11
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S557
G
S
S
S
S
S
K
S
G
M
C
L
V
S
_
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
K524
L
T
M
V
P
S
E
K
E
V
E
P
K
Q
C
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
Dog
Lupus familis
XP_542675
460
51324
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
K557
E
E
A
A
P
T
A
K
S
G
M
C
L
I
S
Rat
Rattus norvegicus
Q63651
564
63750
K557
E
E
A
A
P
T
A
K
S
G
M
C
L
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
S557
E
D
E
T
A
S
S
S
K
S
G
V
C
L
V
Chicken
Gallus gallus
NP_990026
593
64642
R586
P
G
S
G
G
G
T
R
S
A
T
C
G
V
L
Frog
Xenopus laevis
NP_001087513
575
66421
G550
P
S
P
Q
P
K
K
G
L
L
Q
C
F
F
S
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
C678
P
E
P
D
K
A
G
C
F
P
F
R
R
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
N581
I
N
M
D
E
R
R
N
G
T
S
K
P
G
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
S803
K
N
M
N
N
S
H
S
Q
M
D
F
D
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
6.6
0
0
N.A.
0
0
N.A.
13.3
6.6
13.3
0
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
0
0
N.A.
26.6
26.6
N.A.
33.3
6.6
20
0
N.A.
6.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
8
8
16
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
31
8
0
8
% C
% Asp:
0
8
0
16
0
0
0
0
0
0
8
0
8
0
8
% D
% Glu:
24
24
8
0
8
0
8
0
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
8
8
8
8
% F
% Gly:
8
8
0
8
8
8
8
8
16
16
8
0
8
16
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% I
% Lys:
8
0
0
0
8
8
16
24
8
0
0
8
8
8
8
% K
% Leu:
8
0
0
0
0
0
0
0
8
8
0
8
16
8
8
% L
% Met:
0
0
24
0
0
0
0
0
0
16
16
0
0
0
0
% M
% Asn:
0
16
0
8
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
24
0
16
0
31
0
0
0
0
8
0
8
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
8
8
0
0
0
8
8
0
0
% R
% Ser:
0
16
16
8
8
31
8
24
24
8
8
0
0
8
24
% S
% Thr:
0
8
0
8
0
16
8
0
0
8
8
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% _