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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
9.09
Human Site:
T445
Identified Species:
16.67
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
T445
R
L
G
F
R
D
E
T
C
D
K
L
R
A
H
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
T425
S
I
C
R
M
L
L
T
K
N
P
S
K
R
L
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
K227
K
L
N
K
K
R
L
K
K
R
K
G
Y
Q
G
Dog
Lupus familis
XP_542675
460
51324
L359
K
D
I
N
W
R
Q
L
E
A
G
M
L
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
T445
R
L
G
F
R
D
G
T
C
D
A
L
R
A
N
Rat
Rattus norvegicus
Q63651
564
63750
T445
R
L
G
F
R
D
G
T
C
D
A
L
R
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
N445
R
L
G
F
R
N
G
N
C
D
E
L
R
A
N
Chicken
Gallus gallus
NP_990026
593
64642
N475
R
L
G
F
R
D
G
N
C
A
M
L
R
S
Q
Frog
Xenopus laevis
NP_001087513
575
66421
G438
R
L
G
C
Q
G
R
G
A
Q
E
V
K
E
H
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
G332
A
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
R562
R
L
G
C
R
N
G
R
M
G
G
Q
D
V
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
G460
R
V
G
R
P
E
D
G
A
E
E
I
R
A
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
D661
H
R
L
G
A
I
D
D
G
R
E
L
R
A
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
6.6
13.3
0
N.A.
80
80
N.A.
66.6
60
26.6
6.6
N.A.
26.6
N.A.
33.3
N.A.
P-Site Similarity:
100
26.6
26.6
20
N.A.
86.6
86.6
N.A.
86.6
66.6
53.3
13.3
N.A.
33.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
16
16
16
0
0
47
0
% A
% Cys:
0
0
8
16
0
0
0
0
39
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
31
16
8
0
31
0
0
16
0
0
% D
% Glu:
0
0
0
0
0
8
16
0
8
8
31
0
0
8
0
% E
% Phe:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
62
8
0
8
39
24
8
8
16
8
0
0
8
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
31
% H
% Ile:
0
8
8
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
16
0
0
8
8
0
0
8
16
0
16
8
16
0
0
% K
% Leu:
0
62
8
0
8
16
16
8
8
8
0
47
8
0
8
% L
% Met:
0
0
0
0
8
0
0
0
8
0
8
8
0
0
8
% M
% Asn:
0
0
8
8
0
16
0
16
0
8
0
0
0
0
24
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
8
0
0
8
8
8
0
8
8
% Q
% Arg:
62
8
8
16
47
16
8
8
0
16
0
0
54
16
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
31
0
0
0
0
0
8
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _