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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
14.85
Human Site:
T478
Identified Species:
27.22
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
T478
P
F
I
P
D
S
K
T
V
Y
A
K
D
I
Q
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
H445
G
A
A
G
V
K
Q
H
P
V
F
K
D
I
N
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
K244
V
E
K
K
I
L
M
K
V
H
S
R
F
I
V
Dog
Lupus familis
XP_542675
460
51324
Y376
V
P
D
S
R
T
V
Y
A
K
N
I
Q
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
T478
P
F
I
P
D
S
R
T
V
Y
A
K
N
I
Q
Rat
Rattus norvegicus
Q63651
564
63750
T478
P
F
I
P
D
S
R
T
V
Y
A
K
N
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
T478
P
F
I
P
D
S
R
T
V
Y
A
K
N
I
Q
Chicken
Gallus gallus
NP_990026
593
64642
R507
P
F
V
P
D
P
R
R
V
Y
A
K
D
L
G
Frog
Xenopus laevis
NP_001087513
575
66421
A471
P
F
K
P
D
P
Q
A
I
Y
C
K
D
V
L
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
T349
L
G
F
T
D
D
F
T
E
I
K
N
H
M
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
A599
P
F
V
P
D
P
H
A
V
Y
A
K
D
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
A502
P
F
C
P
D
P
R
A
V
Y
A
K
D
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
P724
Q
P
M
M
T
A
T
P
L
S
P
A
M
Q
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
20
13.3
0
N.A.
86.6
86.6
N.A.
86.6
60
46.6
13.3
N.A.
60
N.A.
60
N.A.
P-Site Similarity:
100
26.6
33.3
6.6
N.A.
100
100
N.A.
100
80
66.6
20
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
24
8
0
54
8
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
70
8
0
0
0
0
0
0
47
8
0
% D
% Glu:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
62
8
0
0
0
8
0
0
0
8
0
8
0
8
% F
% Gly:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
31
0
8
0
0
0
8
8
0
8
0
47
0
% I
% Lys:
0
0
16
8
0
8
8
8
0
8
8
70
0
0
0
% K
% Leu:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
24
% L
% Met:
0
0
8
8
0
0
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
24
0
8
% N
% Pro:
62
16
0
62
0
31
0
8
8
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
16
0
0
0
0
0
8
8
31
% Q
% Arg:
0
0
0
0
8
0
39
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
8
0
31
0
0
0
8
8
0
0
0
0
% S
% Thr:
0
0
0
8
8
8
8
39
0
0
0
0
0
0
0
% T
% Val:
16
0
16
0
8
0
8
0
62
8
0
0
0
24
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
62
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _