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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ8
All Species:
24.24
Human Site:
S375
Identified Species:
59.26
UniProt:
Q15842
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15842
NP_004973.1
424
47968
S375
T
L
Q
K
S
E
L
S
H
Q
N
S
L
R
K
Chimpanzee
Pan troglodytes
XP_521849
390
43540
P342
N
T
I
K
V
P
T
P
L
C
T
A
R
Q
L
Rhesus Macaque
Macaca mulatta
XP_001098781
424
47979
S375
T
L
Q
K
S
E
L
S
H
Q
N
S
L
R
K
Dog
Lupus familis
XP_543766
424
47935
S375
T
L
Q
K
S
E
L
S
H
Q
N
S
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P97794
424
47961
S375
T
L
Q
K
S
E
L
S
H
Q
N
S
L
R
K
Rat
Rattus norvegicus
Q63664
424
47944
S375
T
L
Q
K
S
E
L
S
H
Q
N
S
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519724
340
37133
R291
L
R
K
R
N
S
M
R
R
N
N
S
M
R
R
Chicken
Gallus gallus
Q90854
492
55398
N370
L
I
A
P
A
V
S
N
S
K
E
R
N
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025324
416
46812
S367
T
L
Q
K
S
E
L
S
H
Q
N
S
L
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
S409
K
D
Y
Y
C
H
D
S
H
E
H
K
L
E
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
99.7
99.7
N.A.
98.3
97.6
N.A.
67.4
38.8
N.A.
78.5
N.A.
N.A.
N.A.
32.4
N.A.
Protein Similarity:
100
79.9
99.7
100
N.A.
98.5
98.1
N.A.
72.8
58.5
N.A.
87
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
20
0
N.A.
100
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
60
26.6
N.A.
100
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
60
0
0
0
10
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
70
0
10
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
70
0
0
0
0
0
10
0
10
0
0
60
% K
% Leu:
20
60
0
0
0
0
60
0
10
0
0
0
70
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
10
0
0
10
0
10
70
0
10
10
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
60
0
0
0
0
0
0
60
0
0
0
10
0
% Q
% Arg:
0
10
0
10
0
0
0
10
10
0
0
10
10
70
10
% R
% Ser:
0
0
0
0
60
10
10
70
10
0
0
70
0
0
10
% S
% Thr:
60
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _